Last update :
03/05/2024
Various   Theophylline  
Injection
Oral solution
Stability in solutions Stability of mixtures Factors which affect stability Compatibility Route of administration References Pdf
   Chemical structure  

Tradename   Tradename     

Trade names are indicative and excipients composition can be different depending on the country and manufacturers

Aerodyne Austria
Afpred-forte theo Germany
Biofleks Teosel Turkey
Eufilina venosa Spain
Glophyllin India
Polteofilin Turkey
Uniphyllin Greece
Compatibility   Injection   Compatibility : Theophylline              
This screen indicates the compatibilities or incompatibilities with, in this case, the type of incompatibility (precipitation, color change, modification of an emulsion, etc.). The compatibilities shown here are mostly physical only, with the chemical stability of each molecule rarely being assessed. The evaluation of these mixtures was studied to consider the possibility of Y-site administration to the patient. These data cannot be used for making mixtures in advance in bags or syringes. This type of information is available in the screen "Stability in mixture ».
Compound Solvent References
Compatible
Injection Theophylline 1.6 mg/ml
Injection Aciclovir sodium 5 mg/ml
Glucose 5% 336
Compatible
Injection Theophylline 4 mg/ml
Injection Ampicillin sodium 20 mg/ml
None 317
Compatible
Injection Theophylline 4 mg/ml
Injection Ampicillin sodium - sulbactam sodium 30 mg/ml
None 317
Compatible
Injection Theophylline 4 mg/ml
Injection Aztreonam 20 mg/ml
None 317
Compatible
Injection Theophylline 4 mg/ml
Injection Bivalirudin 5 mg/ml
Glucose 5% 1713
Compatible
Injection Theophylline 4 mg/ml
Injection Cefazolin sodium 20 mg/ml
None 317
Compatible
Injection Theophylline 0,8 mg/ml
Injection Cefepime dihydrochloride 4 mg/ml
Glucose 5% 3548
Chemical instability Incompatible
Injection Theophylline 20 mg/ml
Injection Cefepime dihydrochloride 125 mg/ml
Water for Injection 2141
Compatible
Injection Theophylline 4 mg/ml
Injection Ceftazidime 20 mg/ml
None 317
Chemical instability Incompatible
Injection Theophylline 20 mg/ml
Injection Ceftazidime 125 mg/ml
Water for Injection 2141
Chemical instability Incompatible
Injection Theophylline 4 mg/ml
Injection Ceftriaxone disodium 20 & 40 mg/ml
NaCl 0,9% or Glucose 5% 276
Compatible
Injection Theophylline 4 mg/ml
Injection Ceftriaxone disodium 20 mg/ml
None 317
Compatible
Injection Theophylline 0,8 mg/ml
Injection Cefuroxime sodium 7,5 & 15 mg/ml
Glucose 5% 96
Compatible
Injection Theophylline 4 mg/ml
Injection Cimetidine hydrochloride 6 mg/ml
None 317
Compatible
Injection Theophylline 3.2 mg/ml
Injection Cisatracurium besylate 0.1 >> 5 mg/ml
Glucose 5% 299
Compatible
Injection Theophylline 4 mg/ml
Injection Clindamycin phosphate 12 mg/ml
None 317
Compatible
Injection Theophylline 1 mg/ml
Injection Clonidine hydrochloride 0,018 mg/ml
Sodium chloride 0,9% 2018
Compatible
Injection Theophylline 4 mg/ml
Injection Dexamethasone sodium phosphate 0.08 mg/ml
None 317
Compatible
Injection Theophylline 4 mg/ml
Injection Dexmedetomidine 4 µg/ml
Sodium chloride 0,9% 1712
Compatible
Injection Theophylline 0.8 mg/ml
Injection Diltiazem hydrochloride 5 mg/ml
Sodium chloride 0,9% 198
Compatible
Injection Theophylline 4 mg/ml
Injection Dobutamine hydrochloride 1 mg/ml
None 317
Compatible
Injection Theophylline 4 mg/ml
Injection Dopamine hydrochloride 1.6 mg/ml
None 317
Compatible
Injection Theophylline 4 mg/ml
Injection Doxycycline hyclate 1 mg/ml
None 317
Compatible
Injection Theophylline 4 mg/ml
Injection Erythromycin lactobionate 3.3 mg/ml
None 317
Compatible
Injection Theophylline 1.6 mg/ml
Injection Famotidine 0.2 mg/ml
Glucose 5% 398
Compatible
Injection Theophylline 4 mg/ml
Injection Fenoldopam mesylate 80 µg/ml
Sodium chloride 0,9% 1803
Compatible
Injection Theophylline 1,6 mg/ml
Injection Fentanyl citrate 50 µg/ml
Glucose 5% 63
Compatible
Injection Theophylline 4 mg/ml
Injection Fluconazole 2 mg/ml
None 317
Compatible
Injection Theophylline 1,6 mg/ml
Injection Fluconazole 2 mg/ml
Glucose 5% 255
Compatible
Injection Theophylline 4 mg/ml
Injection Gentamicin sulfate 2 mg/ml
None 317
Compatible
Injection Theophylline 1.6 mg/ml
Injection Haloperidol lactate 0.5 & 5 mg/ml
Glucose 5% 403
Compatible
Injection Theophylline 4 mg/ml
Injection Heparin sodium 50 UI/ml
None 317
Compatible
Injection Theophylline 4 mg/ml
Injection Hetastarch 60 mg/ml
Specific solvent 1721
Precipitation after 2 hours Incompatible
Injection Theophylline 4 mg/ml
Injection Hetastarch 60 mg/ml
Sodium chloride 0,9% 472
Compatible
Injection Theophylline 4 mg/ml
Injection Hydrocortisone sodium succinate 2 mg/ml
None 317
Immediate turbidity Incompatible
Injection Theophylline 4 mg/ml
Injection Lansoprazole 0.55 mg/ml
Sodium chloride 0,9% 1625
Compatible
Injection Theophylline 4 mg/ml
Injection Lidocaine hydrochloride 4 mg/ml
None 317
Compatible
Injection Theophylline 4 mg/ml
Injection Linezolid 2 mg/ml
None 1925
Compatible
Injection Theophylline 4 mg/ml
Injection Methylprednisolone sodium succinate 2.5 mg/ml
None 317
Compatible
Injection Theophylline 4 mg/ml
Injection Metronidazole 5 mg/ml
None 317
Compatible
Injection Theophylline 4 mg/ml
Injection Micafungin 1.5 mg/ml
Sodium chloride 0,9% 2108
Compatible
Injection Theophylline 1,6 mg/ml
Injection Midazolam hydrochloride 1 mg/ml
Glucose 5% 176
Compatible
Injection Theophylline 3.2 mg/ml
Injection Milrinone lactate 0.8 mg/ml
Glucose 5% 813
Compatible
Injection Theophylline 4 mg/ml
Injection Nafcillin sodium 20 mg/ml
None 317
Compatible
Injection Theophylline 4 mg/ml
Injection Nitroglycerin 0.2 mg/ml
None 317
Compatible
Injection Theophylline 4 mg/ml
Injection Nitroprusside sodium 0.2 mg/ml
None 317
Compatible
Injection Theophylline 4 mg/ml
Injection Oxaliplatin 0,5 mg/ml
Glucose 5% 1662
Compatible
Injection Theophylline 4 mg/ml
Injection Penicillin G potassium 0.04 MUI/ml
None 317
Immediate precipitation Incompatible
Injection Theophylline 4 mg/ml
Injection Phenytoin sodium 2 mg/ml
None 317
Compatible
Injection Theophylline 4 mg/ml
Injection Piperacillin sodium 60 mg/ml
None 317
Compatible
Injection Theophylline 4 mg/ml
Injection Potassium chloride 200 mEq/l
None 317
Compatible
Injection Theophylline 4 mg/ml
Injection Ranitidine hydrochloride 1 mg/ml
None 317
Compatible
Injection Theophylline 3.2 mg/ml
Injection Remifentanil hydrochloride 25 & 250 µg/ml
Sodium chloride 0,9% 59
Compatible
Injection Theophylline 24 mg/ml
Injection Sugammadex 100 mg/ml
None 3372
Compatible
Injection Theophylline 200 mg/ml
Injection Temocilline 83.33 mg/ml
Water for Injection 2231
Compatible
Injection Theophylline 4 mg/ml
Injection Ticarcillin / clavulanic acid 31 mg/ml
None 317
Compatible
Injection Theophylline
Injection Tigecycline
Sodium chloride 0,9% 3332
Compatible
Injection Theophylline 4 mg/ml
Injection Tobramycin sulfate 0.8 mg/ml
None 317
Unspecified incompatibility Incompatible
Injection Theophylline 20 mg/ml
Injection Vancomycin hydrochloride 10 mg/ml
Glucose 5% 3385
Compatible
Injection Theophylline 4 mg/ml
Injection Vancomycin hydrochloride 6.6 mg/ml
None 317
Compatible
Injection Theophylline 0.4 & 4 mg/ml
Injection Verapamil hydrochloride 0.1 & 0.4 mg/ml
Glucose 5% 372

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