Bibliographie - 266 - Stabilis 4.0

Last update :
28/04/2024

References 266

Type :

Journal

Research teams :

Wilmington - Zeneca Pharma

Authors :

Patel PR.

Title :

Compatibility of meropenem with commonly used injectable drugs.

Reference :

Am J Health-Syst Pharm ; 53: 2853-2855. 1996

Level of Evidence :

Physical stability :

Chemical stability :

Other methods :

Comments :

Not rated: compatibility study only

List of drugs

Aciclovir sodium

	5 mg/ml	+ Meropenem	1 & 50 mg/ml	+
	5 mg/ml	+ Meropenem	20 mg/ml	+

Aminophylline

	1 mg/ml	+ Meropenem	1 & 20 mg/ml	+
	25 mg/ml	+ Meropenem	1 & 50 mg/ml	+

Amphotericin B

	0.2 mg/ml	+ Meropenem	1 & 20 mg/ml	+
	5 mg/ml	+ Meropenem	1 & 50 mg/ml	+

Atenolol

0.5 mg/ml

Meropenem

1 & 50 mg/ml

Atropine sulfate

	0.4 mg/ml	+ Meropenem	1 & 50 mg/ml	+
	0.04 mg/ml	+ Meropenem	1 & 20 mg/ml	+

Calcium gluconate

1 mg/ml	+ Meropenem	1 & 20 mg/ml	+
4 mg/ml	+ Meropenem	50 mg/ml	+
4 mg/ml	+ Meropenem	1 mg/ml	+

Cimetidine hydrochloride

	3 mg/ml	+ Meropenem	1 & 20 mg/ml	+
	150 mg/ml	+ Meropenem	1 & 50 mg/ml	+

Dexamethasone sodium phosphate

	10 mg/ml	+ Meropenem	1 & 50 mg/ml	+
	4 mg/ml	+ Meropenem	1 & 20 mg/ml	+

Diazepam

5 mg/ml

Meropenem

1 & 50 mg/ml

Digoxin

250 µg/ml

Meropenem

1 & 50 mg/ml

Diphenhydramine hydrochloride

	0.08 mg/ml	+ Meropenem	1 & 20 mg/ml	+
	50 mg/ml	+ Meropenem	1 & 50 mg/ml	+

Dobutamine hydrochloride

1 mg/ml

Meropenem

1 & 20 mg/ml

Dopamine hydrochloride

0.8 mg/ml

Meropenem

1 & 20 mg/ml

Doxycycline hyclate

	0,2 & 1 mg/ml	+ Meropenem	20 & 50 mg/ml	+
	0.2 & 1 mg/ml	+ Meropenem	1 mg/ml	+

Enalaprilate

0.05 mg/ml

Meropenem

1 >> 50 mg/ml

Fluconazole

2 mg/ml

Meropenem

1 >> 50 mg/ml

Furosemide

	1 mg/ml	+ Meropenem	1 & 20 mg/ml	+
	10 mg/ml	+ Meropenem	1 & 50 mg/ml	+

Gentamicin sulfate

	0.8 mg/ml	+ Meropenem	1 & 20 mg/ml	+
	4 mg/ml	+ Meropenem	1 & 50 mg/ml	+

Heparin sodium

	20 UI/ml	+ Meropenem	1 & 20 mg/ml	+
	1 UI/ml	+ Meropenem	1 & 50 mg/ml	+

Insulin

	0.2 UI/ml	+ Meropenem	1 & 50 mg/ml	+
	1 UI/ml	+ Meropenem	1 & 20 mg/ml	+

Magnesium sulfate

1 mg/ml

Meropenem

1 & 20 mg/ml

Meropenem

1 & 50 mg/ml	+ Aciclovir sodium	5 mg/ml	+
20 mg/ml	+ Aciclovir sodium	5 mg/ml	+
1 & 20 mg/ml	+ Aminophylline	1 mg/ml	+
1 & 50 mg/ml	+ Aminophylline	25 mg/ml	+
1 & 20 mg/ml	+ Amphotericin B	0.2 mg/ml	+
1 & 50 mg/ml	+ Amphotericin B	5 mg/ml	+
1 & 50 mg/ml	+ Atenolol	0.5 mg/ml	+
1 & 20 mg/ml	+ Atropine sulfate	0.04 mg/ml	+
1 & 50 mg/ml	+ Atropine sulfate	0.4 mg/ml	+
1 & 20 mg/ml	+ Calcium gluconate	1 mg/ml	+
50 mg/ml	+ Calcium gluconate	4 mg/ml	+
1 mg/ml	+ Calcium gluconate	4 mg/ml	+
1 & 20 mg/ml	+ Cimetidine hydrochloride	3 mg/ml	+
1 & 50 mg/ml	+ Cimetidine hydrochloride	150 mg/ml	+
1 & 50 mg/ml	+ Dexamethasone sodium phosphate	10 mg/ml	+
1 & 20 mg/ml	+ Dexamethasone sodium phosphate	4 mg/ml	+
1 & 50 mg/ml	+ Diazepam	5 mg/ml	+
1 & 50 mg/ml	+ Digoxin	250 µg/ml	+
1 & 20 mg/ml	+ Diphenhydramine hydrochloride	0.08 mg/ml	+
1 & 50 mg/ml	+ Diphenhydramine hydrochloride	50 mg/ml	+
1 & 20 mg/ml	+ Dobutamine hydrochloride	1 mg/ml	+
1 & 20 mg/ml	+ Dopamine hydrochloride	0.8 mg/ml	+
20 & 50 mg/ml	+ Doxycycline hyclate	0,2 & 1 mg/ml	+
1 mg/ml	+ Doxycycline hyclate	0.2 & 1 mg/ml	+
1 >> 50 mg/ml	+ Enalaprilate	0.05 mg/ml	+
1 >> 50 mg/ml	+ Fluconazole	2 mg/ml	+
1 & 50 mg/ml	+ Furosemide	10 mg/ml	+
1 & 20 mg/ml	+ Furosemide	1 mg/ml	+
1 & 50 mg/ml	+ Gentamicin sulfate	4 mg/ml	+
1 & 20 mg/ml	+ Gentamicin sulfate	0.8 mg/ml	+
1 & 50 mg/ml	+ Heparin sodium	1 UI/ml	+
1 & 20 mg/ml	+ Heparin sodium	20 UI/ml	+
1 & 20 mg/ml	+ Insulin	1 UI/ml	+
1 & 50 mg/ml	+ Insulin	0.2 UI/ml	+
1 & 20 mg/ml	+ Magnesium sulfate	1 mg/ml	+
1 & 20 mg/ml	+ Metoclopramide hydrochloride	0.1 mg/ml	+
1 & 50 mg/ml	+ Metoclopramide hydrochloride	5 mg/ml	+
1 >> 50 mg/ml	+ Metronidazole	5 mg/ml	+
1 >> 50 mg/ml	+ Morphine sulfate	1 mg/ml	+
1 & 20 mg/ml	+ Norepinephrine bitartrate	8 mg/ml	+
1 & 50 mg/ml	+ Norepinephrine bitartrate	1 mg/ml	+
1 mg/ml	+ Ondansetron hydrochloride	1 mg/ml	+
20 & 50 mg/ml	+ Ondansetron hydrochloride	1 mg/ml	+
1 & 20 mg/ml	+ Phenobarbital sodium	0.2 mg/ml	+
1 & 50 mg/ml	+ Phenobarbital sodium	0.32 mg/ml	+
1 & 20 mg/ml	+ Ranitidine hydrochloride	0.1 mg/ml	+
1 & 20 mg/ml	+ Vancomycin hydrochloride	1 mg/ml	+
1 & 50 mg/ml	+ Vancomycin hydrochloride	5 mg/ml	+
1 mg/ml	+ Zidovudine	4 mg/ml	+
20 & 50 mg/ml	+ Zidovudine	4 mg/ml	+

Metoclopramide hydrochloride

	5 mg/ml	+ Meropenem	1 & 50 mg/ml	+
	0.1 mg/ml	+ Meropenem	1 & 20 mg/ml	+

Metronidazole

5 mg/ml

Meropenem

1 >> 50 mg/ml

Morphine sulfate

1 mg/ml

Meropenem

1 >> 50 mg/ml

Norepinephrine bitartrate

	8 mg/ml	+ Meropenem	1 & 20 mg/ml	+
	1 mg/ml	+ Meropenem	1 & 50 mg/ml	+

Ondansetron hydrochloride

	1 mg/ml	+ Meropenem	1 mg/ml	+
	1 mg/ml	+ Meropenem	20 & 50 mg/ml	+

Phenobarbital sodium

	0.2 mg/ml	+ Meropenem	1 & 20 mg/ml	+
	0.32 mg/ml	+ Meropenem	1 & 50 mg/ml	+

Ranitidine hydrochloride

0.1 mg/ml

Meropenem

1 & 20 mg/ml

Vancomycin hydrochloride

	1 mg/ml	+ Meropenem	1 & 20 mg/ml	+
	5 mg/ml	+ Meropenem	1 & 50 mg/ml	+

Zidovudine

	4 mg/ml	+ Meropenem	1 mg/ml	+
	4 mg/ml	+ Meropenem	20 & 50 mg/ml	+

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