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References 4664
Type :
Journal
Web link :
https://doi.org/10.1002/bmc.5340
Research teams :
Innsbruck - Institute of Analytical Chemistry and Radiochemistry, Leopold-Franzens University of Innsbruck
Authors :
Harder M, Fiegl-Lechner A, Oberacher H, Horvath U.E.I, Schlager A, Jeske M, Kerndler S, Schüllner F, Bonn G.F, Rainer M.
Title :
Stability evaluation of morphine, hydromorphone, metamizole and esketamine containing analgesic mixtures applied for patient-controlled analgesia in hospice and palliative care.
Reference :
Biomed Chromatogr ;e5340. 2022
Level of Evidence :
Physical stability :
Chemical stability :
Other methods :
Comments :
Stability indicating capability inadequately assessed
No visual inspection
Results with high coefficient of variation or not provided, or lack of duplicate analysis of each point
Degradation products quantified but not identified
List of drugs
Esketamine
Hydromorphone hydrochloride
20 mg/ml
22°C
7
20 mg/ml
37°C
7
Metamizol sodium
Morphine hydrochloride
25 mg/ml
22°C
7
25 mg/ml
37°C
7
22°C
Hydromorphone hydrochloride
20 mg/ml
Esketamine
20 mg/ml
7
22°C
Morphine hydrochloride
25 mg/ml
Esketamine
20 mg/ml
Metamizol sodium
50 mg/ml
7
22°C
Morphine hydrochloride
25 mg/ml
Metamizol sodium
50 mg/ml
7
37°C
Hydromorphone hydrochloride
20 mg/ml
Esketamine
20 mg/ml
7
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