Last update :
15/10/2021
Antiepileptic   Levetiracetam  
Injection
Oral solution
Stability in solutions Stability of mixtures Factors which affect stability Compatibility Route of administration References Pdf
   Chemical structure  

Tradename   Tradename     

Trade names are indicative and excipients composition can be different depending on the country and manufacturers

Callexe Argentina
Ceumid Chile, Ecuador
Epilem Turkey
Keppra Argentina, Belgium, Colombia, Germany, Great Britain, Iceland, India, Italy, Mexico, Norway, Portugal, Romania, Spain, Switzerland, Turkey, United States of America
Kevesy Germany
Levetam Turkey
Levetiracetam Belgium, Germany, Great Britain, Spain
Levip Germany
Netrolex Turkey
Prepalepan Romania
Tirgen Turkey
Compatibility   Injection   Compatibility : Levetiracetam        
This screen indicates the compatibilities or incompatibilities with, in this case, the type of incompatibility (precipitation, color change, modification of an emulsion, etc.). The compatibilities shown here are mostly physical only, with the chemical stability of each molecule rarely being assessed. The evaluation of these mixtures was studied to consider the possibility of Y-site administration to the patient. These data cannot be used for making mixtures in advance in bags or syringes. This type of information is available in the screen "Stability in mixture ».
Compound Solvent References
Compatible
Injection Levetiracetam 5.21 & 20.83 mg/ml
Injection Cefazolin sodium 41.6 mg/ml
NaCl 0,9% or Glucose 5% 4254
Compatible
Injection Levetiracetam 20.83 mg/ml
Injection Cefotaxime sodium 83.3 mg/ml
NaCl 0,9% or Glucose 5% 4254
Compatible
Injection Levetiracetam 5 mg/ml
Injection Cisatracurium besylate 1 mg/ml
Sodium chloride 0,9% 4569
Compatible
Injection Levetiracetam 5 mg/ml
Injection Dexmedetomidine 4 µg/ml
Sodium chloride 0,9% 4569
Turbidity in one hour Incompatible
Injection Levetiracetam 100 mg/ml
Injection Dobutamine hydrochloride 2 mg/ml
Glucose 5% 4108
Turbidity in one hour Incompatible
Injection Levetiracetam 10 mg/ml
Injection Dopamine hydrochloride 1.6 mg/ml
Glucose 5% 4108
Compatible
Injection Levetiracetam 5 mg/ml
Injection Fosphenytoin sodium 15 mg/ml
Sodium chloride 0,9% 4569
Turbidity in 4 hours Incompatible
Injection Levetiracetam 100 mg/ml
Injection Heparin sodium 100 UI/ml
Glucose 5% 4108
Compatible
Injection Levetiracetam 5 mg/ml
Injection Insulin aspart 1 UI/ml
NaCl 0,9% or Glucose 5% 1508
Compatible
Injection Levetiracetam 5 mg/ml
Injection Norepinephrine bitartrate 0,016 >>0,064 mg/ml
Sodium chloride 0,9% 4569
Compatible
Injection Levetiracetam 5 mg/ml
Injection Pentoxifyllin 5 mg/ml
Sodium chloride 0,9% 4543
Compatible
Injection Levetiracetam 5 mg/ml
Injection Piperacillin sodium / tazobactam 33,75 mg/ml
Sodium chloride 0,9% 4569
Subvisual incompatibility Incompatible
Injection Levetiracetam 5 mg/ml
Injection Piperacillin sodium / tazobactam 45 mg/ml
Sodium chloride 0,9% 4569
Compatible
Injection Levetiracetam 20.83 mg/ml
Injection Piperacillin sodium / tazobactam 166/20.83 mg/ml
NaCl 0,9% or Glucose 5% 4254
Immediate precipitation Incompatible
Injection Levetiracetam 5 mg/ml
Injection Posaconazole 1,2 mg/ml
Sodium chloride 0,9% 4521
Compatible
Injection Levetiracetam 5 mg/ml
Injection Propofol 10 mg/ml
Sodium chloride 0,9% 4569
Compatible
Injection Levetiracetam 5 mg/ml
Injection Vancomycin hydrochloride 5 mg/ml
Sodium chloride 0,9% 4569
Compatible
Injection Levetiracetam 5 mg/ml
Injection Vasopressin 1 UI/ml
Sodium chloride 0,9% 4569
Compatible
Injection Levetiracetam 0.4 >> 4.8 mg/ml
Parenteral nutrition (with lipids) 3919

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