Last update :
10/08/2022
Antifungal   Posaconazole  
Injection
Stability in solutions Stability of mixtures Factors which affect stability Compatibility Route of administration References Pdf
   Chemical structure  

Tradename   Tradename     

Trade names are indicative and excipients composition can be different depending on the country and manufacturers

Noxafil Argentina, France, Germany, Great Britain, Romania, Switzerland, United States of America
Posanol Canada
Compatibility   Injection   Compatibility : Posaconazole              
This screen indicates the compatibilities or incompatibilities with, in this case, the type of incompatibility (precipitation, color change, modification of an emulsion, etc.). The compatibilities shown here are mostly physical only, with the chemical stability of each molecule rarely being assessed. The evaluation of these mixtures was studied to consider the possibility of Y-site administration to the patient. These data cannot be used for making mixtures in advance in bags or syringes. This type of information is available in the screen "Stability in mixture ».
Compound Solvent References
Immediate precipitation Incompatible
Injection Posaconazole 1,2 mg/ml
Injection Aciclovir sodium 3,5 mg/ml
Sodium chloride 0,9% 4521
Precipitation after 1 hour Incompatible
Injection Posaconazole 1,2 mg/ml
Injection Alizapride hydrochloride 3 mg/ml
Sodium chloride 0,9% 4521
Compatible
Injection Posaconazole
Injection Amikacin sulfate
4380
Compatible
Injection Posaconazole
Injection Caspofungin acetate
4380
Immediate precipitation Incompatible
Injection Posaconazole 1,2 mg/ml
Injection Cefepime dihydrochloride 40 mg/ml
Sodium chloride 0,9% 4521
Immediate precipitation Incompatible
Injection Posaconazole 2 mg/ml
Injection Cefiderocol sulfate tosylate 20 mg/mL
NaCl 0,9% or Glucose 5% 4528
Compatible
Injection Posaconazole
Injection Ciprofloxacin lactate
4380
Compatible
Injection Posaconazole
Injection Daptomycin
4380
Compatible
Injection Posaconazole
Injection Dobutamine hydrochloride
4380
Compatible
Injection Posaconazole
Injection Famotidine
4380
Compatible
Injection Posaconazole
Injection Filgrastim
4380
Unspecified incompatibility Incompatible
Injection Posaconazole
Ringer’s lactate solution 4380
Compatible
Injection Posaconazole 1,2 mg/ml
Injection Filgrastim 3 µg/ml
Sodium chloride 0,9% 4521
Immediate precipitation Incompatible
Injection Posaconazole 1,2 mg/ml
Injection Furosemide 0,8 mg/ml
Sodium chloride 0,9% 4521
Immediate precipitation Incompatible
Injection Posaconazole 1,2 mg/ml
Injection Ganciclovir sodium 3,5 mg/ml
Sodium chloride 0,9% 4521
Unspecified incompatibility Incompatible
Injection Posaconazole
NaHCO3 4380
Compatible
Injection Posaconazole
Injection Gentamicin sulfate
4380
Compatible
Injection Posaconazole
Injection Hydromorphone hydrochloride
4380
Immediate precipitation Incompatible
Injection Posaconazole 1,2 mg/ml
Injection Insulin aspart 100 UI/ml
Sodium chloride 0,9% 4521
Immediate precipitation Incompatible
Injection Posaconazole 1,2 mg/ml
Injection Levetiracetam 5 mg/ml
Sodium chloride 0,9% 4521
Compatible
Injection Posaconazole
Injection Levofloxacine
4380
Compatible
Injection Posaconazole
Injection Lorazepam
4380
Compatible
Injection Posaconazole
Injection Meropenem
4380
Immediate precipitation Incompatible
Injection Posaconazole 1,2 mg/ml
Injection Methylprednisolone sodium succinate 0,4 mg/ml
Sodium chloride 0,9% 4521
Immediate precipitation Incompatible
Injection Posaconazole 1,2 mg/ml
Injection Methylprednisolone sodium succinate 20 mg/ml
Sodium chloride 0,9% 4521
Precipitation after 4 hours Incompatible
Injection Posaconazole 1,2 mg/ml
Injection Metoclopramide hydrochloride 0,1 mg/ml
Sodium chloride 0,9% 4521
Compatible
Injection Posaconazole
Injection Micafungin
4380
Compatible
Injection Posaconazole
Injection Morphine sulfate
4380
Immediate precipitation Incompatible
Injection Posaconazole 1,2 mg/ml
Injection Nefopam 0,2 mg/ml
Sodium chloride 0,9% 4521
Immediate precipitation Incompatible
Injection Posaconazole 1,2 mg/ml
Injection Nefopam 2,5 mg/ml
Sodium chloride 0,9% 4521
Compatible
Injection Posaconazole
Injection Norepinephrine bitartrate
4380
Precipitation after 1 hour Incompatible
Injection Posaconazole 1,2 mg/ml
Injection Ondansetron hydrochloride 0,14 mg/ml
Sodium chloride 0,9% 4521
Precipitation after 1 hour Incompatible
Injection Posaconazole 1,2 mg/ml
Injection Ondansetron hydrochloride 0,48 mg/ml
Sodium chloride 0,9% 4521
Immediate precipitation Incompatible
Injection Posaconazole 1,2 mg/ml
Injection Pantoprazole sodium 0,4 mg/ml
Sodium chloride 0,9% 4521
Immediate precipitation Incompatible
Injection Posaconazole 1,2 mg/ml
Injection Paracetamol 10 mg/ml
Sodium chloride 0,9% 4521
Immediate precipitation Incompatible
Injection Posaconazole 1,2 mg/ml
Injection Phloroglucinol 0,8 mg/ml
Sodium chloride 0,9% 4521
Immediate precipitation Incompatible
Injection Posaconazole 1,2 mg/ml
Injection Piperacillin sodium / tazobactam 160 mg/ml
Sodium chloride 0,9% 4521
Immediate precipitation Incompatible
Injection Posaconazole 1,2 mg/ml
Injection Potassium chloride 1341 mEq/l
Sodium chloride 0,9% 4521
Compatible
Injection Posaconazole
Injection Potassium chloride
4380
Compatible
Injection Posaconazole 1,2 mg/ml
Injection Tacrolimus 3 µg/ml
Sodium chloride 0,9% 4521
Compatible
Injection Posaconazole 1,2 mg/ml
Injection Tacrolimus 30 µg/ml
Sodium chloride 0,9% 4521
Immediate precipitation Incompatible
Injection Posaconazole 1,2 mg/ml
Injection Tramadol hydrochloride 0,5 mg/ml
Sodium chloride 0,9% 4521
Compatible
Injection Posaconazole
Injection Vancomycin hydrochloride
4380

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