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References   References 2001  
Type : Journal
Research teams : Stockport - Stepping Hill Hospital, Quality Control North Wes
Authors : Rigge DC, Jones MF.
Title : Shelf lives of aseptically prepared medicines - stability of hydrocortisone sodium succinate in PVC and non-PVC bags and in polypropylene syringes.
Reference : J Pharm Biomed Anal ; 38: 332-336. 2005
Level of Evidence : 
Level of evidence B
Physical stability : 
Visual examination 
Chemical stability : 
High Performance Liquid Chromatography - ultraviolet detector (HPLC-UV)
Stability defined as 90% of the initial concentration
Other methods : 
Mass balance PH measurement 
Comments : 
List of drugs
InjectionHydrocortisone sodium succinate Anti-inflammatory
Stability in solutions Polyvinyl chloride Sodium chloride 0,9% 1 mg/ml 25°C Light
2 Day
Stability in solutions Polyvinyl chloride Sodium chloride 0,9% 1 mg/ml 7°C Not specified
15 Day
Stability in solutions Polyolefine Sodium chloride 0,9% 1 mg/ml 7°C Not specified
15 Day
Stability in solutions Polypropylen Syringe Water for Injection 50 mg/ml 25°C Light
15 Day
Stability in solutions Polypropylen Syringe Water for Injection 50 mg/ml 5°C Not specified
120 Day
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