Last update :
16/06/2024
References   References 192  
Type : Journal

Research teams : Omaha - University of Nebraska Medical center, College of pharmacy
Authors : Peddicord TE, Olsen KM, ZumBrunnen TL, Warner DJ, Webb L.
Title : Stability of high-concentration dopamine hydrochloride, norepinephrine bitartrate, epinephrine hydrochloride, and nitroglycerin in 5% dextrose injection.
Reference : Am J Health-Syst Pharm ; 54: 1417-1419. 1997

Level of Evidence : 
Level of evidence B
Physical stability : 
Chemical stability : 
High Performance Liquid Chromatography - ultraviolet detector (HPLC-UV)
Stability defined as 95% of the initial concentration
Other methods : 
Comments : 
No visual inspection

List of drugs
InjectionDopamine hydrochloride Cardiotonic
Stability in solutions Polyvinyl chloride Glucose 5% 6,4 mg/ml 23°C Light
24 Hour
InjectionEpinephrine hydrochloride Sympathomimetic
Stability in solutions Polyvinyl chloride Glucose 5% 100 µg/ml 23°C Protect from light
24 Hour
InjectionNitroglycerin Vasodilator
Stability in solutions Glass Glucose 5% 1 mg/ml 23°C Light
24 Hour
InjectionNorepinephrine bitartrate Sympathomimetic
Stability in solutions Polyvinyl chloride Glucose 5% 0,064 mg/ml 23°C Protect from light
24 Hour

  Mentions Légales