Last update :
24/11/2020
References   References 4479  
Type : Journal

Research teams : Mont Godinne - Drug Stability Research Group (DSRG) - CHU UCL NAMUR, site de Godinne
Authors : Closset M, Goderniaux N, Colsoul M-L, Soumoy L, Bihin B, Jamart J, Odou P, Hecq J-D, galanti L.
Title : Long term stability of an admixture of alizapride and ondansetron in 0.9% sodium chloride solution polyolefin bags stored at 5 +/- 3°C.
Reference : J Oncol Pharm Practice 2020

Level of Evidence : 
Level of evidence D
Physical stability : 
Visual examination Turbidimetry 
Chemical stability : 
High Performance Liquid Chromatography - ultraviolet detector (HPLC-UV)
Other methods : 
PH measurement 
Comments : 
Stability indicating capability inadequately assessed

List of drugs
InjectionAlizapride hydrochloride Antiemetic
InjectionOndansetron hydrochloride Antiemetic
Stability of mixtures
Polyolefine Sodium chloride 0,9% 2-8°C Not specified
Injection Alizapride hydrochloride 0,926 mg/ml
Injection Ondansetron hydrochloride 0,074 mg/ml
56 Day

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