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References   References 4428  
Type : Journal
Web link : https://doi.org/10.5863/1551-6776-9.2.126
Research teams : Memphis - University of Tennessee, College of Pharmacy
Authors : Rashed S.M, Sweatman T.W, Thoma L, Hovinga C.A, Phelps S.J.
Title : Chemical Compatibility of Depacon® with Medications Frequently Administered by Intravenous Y-Site Delivery in Patients with Epilepsy or Head Trauma.
Reference : J Pediatr Pharmacol Ther ; 9, 2: 126-132. 2004
Level of Evidence : 
Physical stability : 
Chemical stability : 
Other methods : 
Comments : 
List of drugs
InjectionAtracurium besylate Curarimimetic
Compatible 0.2 mg/ml + InjectionValproic acid 2 & 20 mg/ml + NaCl 0,9% or Glucose 5%
InjectionDexamethasone sodium phosphate Anti-inflammatory
Compatible 0.64 mg/ml + InjectionValproic acid 2 & 20 mg/ml + NaCl 0,9% or Glucose 5%
InjectionDiazepam Anxiolytic
Incompatible 5 mg/ml + InjectionValproic acid 2 & 20 mg/ml + NaCl 0,9% or Glucose 5%
InjectionFosphenytoin sodium Antiepileptic
Compatible + InjectionValproic acid 2 & 20 mg/ml + NaCl 0,9% or Glucose 5%
InjectionLorazepam Anxiolytic
Compatible 1 mg/ml + InjectionValproic acid 2 & 20 mg/ml + NaCl 0,9% or Glucose 5%
InjectionMagnesium sulfate Electrolyte
Compatible 100 mg/ml + InjectionValproic acid 2 & 20 mg/ml + NaCl 0,9% or Glucose 5%
InjectionMannitol Various
Compatible 150 mg/ml + InjectionValproic acid 2 & 20 mg/ml + NaCl 0,9% or Glucose 5%
InjectionMethylprednisolone sodium succinate Anti-inflammatory
Compatible 5 mg/ml + InjectionValproic acid 2 & 20 mg/ml + NaCl 0,9% or Glucose 5%
InjectionMidazolam hydrochloride Anxiolytic
Incompatible 2 mg/ml + InjectionValproic acid 2 & 20 mg/ml + NaCl 0,9% or Glucose 5%
InjectionPentobarbital sodium General anesthetic
Compatible 5 mg/ml + InjectionValproic acid 2 & 20 mg/ml + NaCl 0,9% or Glucose 5%
InjectionPhenytoin sodium Antiepileptic
Incompatible 50 mg/ml + InjectionValproic acid 2 & 20 mg/ml + NaCl 0,9% or Glucose 5%
InjectionRanitidine hydrochloride Antihistamine (H2)
Compatible 25 mg/ml + InjectionValproic acid 2 & 20 mg/ml + NaCl 0,9% or Glucose 5%
InjectionThiopental sodium General anesthetic
Compatible 25 mg/ml + InjectionValproic acid 2 & 20 mg/ml + NaCl 0,9% or Glucose 5%
InjectionValproic acid Antiepileptic
Compatible 2 & 20 mg/ml + InjectionAtracurium besylate 0.2 mg/ml + NaCl 0,9% or Glucose 5%
Compatible 2 & 20 mg/ml + InjectionDexamethasone sodium phosphate 0.64 mg/ml + NaCl 0,9% or Glucose 5%
Incompatible 2 & 20 mg/ml + InjectionDiazepam 5 mg/ml + NaCl 0,9% or Glucose 5%
Compatible 2 & 20 mg/ml + InjectionFosphenytoin sodium + NaCl 0,9% or Glucose 5%
Compatible 2 & 20 mg/ml + InjectionLorazepam 1 mg/ml + NaCl 0,9% or Glucose 5%
Compatible 2 & 20 mg/ml + InjectionMagnesium sulfate 100 mg/ml + NaCl 0,9% or Glucose 5%
Compatible 2 & 20 mg/ml + InjectionMannitol 150 mg/ml + NaCl 0,9% or Glucose 5%
Compatible 2 & 20 mg/ml + InjectionMethylprednisolone sodium succinate 5 mg/ml + NaCl 0,9% or Glucose 5%
Incompatible 2 & 20 mg/ml + InjectionMidazolam hydrochloride 2 mg/ml + NaCl 0,9% or Glucose 5%
Compatible 2 & 20 mg/ml + InjectionPentobarbital sodium 5 mg/ml + NaCl 0,9% or Glucose 5%
Incompatible 2 & 20 mg/ml + InjectionPhenytoin sodium 50 mg/ml + NaCl 0,9% or Glucose 5%
Compatible 2 & 20 mg/ml + InjectionRanitidine hydrochloride 25 mg/ml + NaCl 0,9% or Glucose 5%
Compatible 2 & 20 mg/ml + InjectionThiopental sodium 25 mg/ml + NaCl 0,9% or Glucose 5%
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