Last update :
15/10/2021
References   References 350  
Type : Journal

Research teams : Amsterdam - Free University Hospital, Department of Pharmacy
Authors : Martens HJ, De Goede PN, Van Loenen AC.
Title : Sorption of various drugs in polyvinyl chloride, glass, and polyethylene-lined infusion containers.
Reference : Am J Hosp Pharm ; 47: 369-373. 1990

Level of Evidence : 
Physical stability : 
Chemical stability : 
Other methods : 
Comments : 

List of drugs
InjectionChloroquine sulfate Antiparasitic
Stability in solutions Glass Sodium chloride 0,9% 0,48 mg/ml 21°C Protect from light
24 Hour
Stability in solutions Polyvinyl chloride Sodium chloride 0,9% 0,48 mg/ml 21°C Protect from light
24 Hour
Stability in solutions Polyethylene Sodium chloride 0,9% 0,48 mg/ml 21°C Protect from light
24 Hour
InjectionDiazepam Anxiolytic
Factors which affect stability Container Polyvinyl chloride Induces Absorption
Stability in solutions Glass Sodium chloride 0,9% 0,038 mg/ml 21°C Protect from light
24 Hour
Stability in solutions Polyethylene Sodium chloride 0,9% 0,038 mg/ml 21°C Protect from light
24 Hour
InjectionIsosorbide dinitrate Vasodilator
Factors which affect stability Container Polyvinyl chloride Induces Absorption
Stability in solutions Glass Sodium chloride 0,9% 0,095 mg/ml 21°C Protect from light
24 Hour
Stability in solutions Polyethylene Sodium chloride 0,9% 0,095 mg/ml 21°C Protect from light
24 Hour
InjectionLorazepam Anxiolytic
Stability in solutions Glass Sodium chloride 0,9% 0,038 mg/ml 21°C Protect from light
24 Hour
Stability in solutions Polyvinyl chloride Sodium chloride 0,9% 0,038 mg/ml 21°C Protect from light
24 Hour
Stability in solutions Polyethylene Sodium chloride 0,9% 0,038 mg/ml 21°C Protect from light
24 Hour
InjectionMidazolam hydrochloride Anxiolytic
Stability in solutions Glass Sodium chloride 0,9% 0,036 mg/ml 21°C Protect from light
24 Hour
Stability in solutions Polyvinyl chloride Sodium chloride 0,9% 0,036 mg/ml 21°C Protect from light
24 Hour
Stability in solutions Polyethylene Sodium chloride 0,9% 0,036 mg/ml 21°C Protect from light
24 Hour
InjectionNitroglycerin Vasodilator
Factors which affect stability Container Polyvinyl chloride Induces Absorption
Stability in solutions Glass Sodium chloride 0,9% 0,1 mg/ml 21°C Protect from light
24 Hour
Stability in solutions Polyethylene Sodium chloride 0,9% 0,1 mg/ml 21°C Protect from light
24 Hour
InjectionPromethazine hydrochloride Antihistamine (H1)
Stability in solutions Glass Sodium chloride 0,9% 0,095 mg/ml 21°C Protect from light
24 Hour
Stability in solutions Polyvinyl chloride Sodium chloride 0,9% 0,095 mg/ml 21°C Protect from light
24 Hour
Stability in solutions Polyethylene Sodium chloride 0,9% 0,095 mg/ml 21°C Protect from light
24 Hour
InjectionThiopental sodium General anesthetic
Stability in solutions Glass Sodium chloride 0,9% 1,8 mg/ml 21°C Protect from light
24 Hour
Stability in solutions Polyvinyl chloride Sodium chloride 0,9% 1,8 mg/ml 21°C Protect from light
24 Hour
Stability in solutions Polyethylene Sodium chloride 0,9% 1,8 mg/ml 21°C Protect from light
24 Hour
InjectionWarfarin sodium Anticoagulant
Factors which affect stability Container Polyvinyl chloride Induces Absorption
Stability in solutions Glass Sodium chloride 0,9% 0,010 mg/ml 21°C Protect from light
24 Hour
Stability in solutions Polyethylene Sodium chloride 0,9% 0,010 mg/ml 21°C Protect from light
24 Hour

  Mentions Légales