Dernière mise à jour :
26/03/2024
Antihypertenseur   Clonidine hydrochloride  
Injectable
Gélule Sachet papier Solution buvable
Stabilité des solutions Stabilité en mélange Facteur influençant la stabilité Compatibilités Voie d’administration Bibliographie Pdf
   Structure chimique  

Noms commerciaux   Noms commerciaux     

Les noms commerciaux sont donnés à titre indicatif et la composition en excipients peut être différente selon les pays et selon les laboratoires

Catapres Australie, Grande Bretagne, Irlande, Nouvelle Zélande
Catapresan Allemagne, Autriche, Espagne, Finlande, Grèce, Italie, Pays bas, Suède, Suisse, Vénézuela
Catapressan Belgique, France, Luxembourg, Maroc, Tunisie
Clonidin Allemagne, Brésil
Clonidina Argentine, Chili, Espagne, Vénézuela
Clonipres Vénézuela
Haemiton Allemagne
Lowpres Vénézuela
Paracefan Allemagne
Bibliographie   Injectable   Bibliographie : Clonidine hydrochloride  
Type Source
186 Revue Swart EL, Mooren RAG, Van Loenen AC.
Compatibility of midazolam hydrochloride and lorazepam with selected drugs during simulated Y-site administration.
Am J Health-Syst Pharm 1995 ; 52: 2020-2022.
346 Revue Wulf H, Gleim M, Mignat C.
The stability of mixtures of morphine hydrochloride, bupivacaine hydrochloride, and clonidine hydrochloride in portable pump reservoirs for the management of chronic pain syndromes.
J Pain Symptom Manage 1994 ; 9: 308-311.
650 Revue Trissel LA, Hassenbusch SJ.
Development of clonidine hydrochloride injections for epidural and intrathecal administration.
Int J Pharm Compound 1997 ; 1: 274-277.
1506 Revue Lopez-Cabezas C, Guerrero L, Molas G, Anglada H, Soy D.
Physicochemical compatibility of high concentration drugs usually Y-site administered in intensive care units.
EJHP 2015 ;22:107-112.
1508 Revue Voirol P, Berger-Gryllaki M, Pannatier A, Eggimann P, Sadeghipour F.
Visual compatibility of insulin aspart with intravenous drugs frequently used in ICU.
EJHP 2015 ;22:123-124.
1516 Laboratoire Ropivacaine (Naropeine®) - Summary of Product Characteristics
Mercury Pharmaceuticals Limited 2012
1601 Revue Godwin DA, Kim NH, Zuniga R.
Stability of a baclofen and clonidine hydrochloride admixture for intrathecal administration.
Hosp Pharm 2001 ; 36: 950-954.
1665 Revue Öster Svedberg K, McKenzie J, Larrivee-Elkins C.
Compatibility of ropivacaine with morphine, sufentanil, fentanyl, or clonidine.
J Clin Pharm Ther 2002 ; 21: 39-45.
1708 Revue Xu QA, Trissel LA, Pham L.
Physical and chemical stability of low and high concentrations of morphine sulfate with clonidine hydrochloride packaged in plastic syringes.
Int J Pharm Compound 2002 ; 6: 66-69.
1869 Revue Hildebrand KR, Elsberry DD, Hassenbusch SJ.
Stability and compatibility of morphine-clonidine admixtures in an implantable infusion system.
J Pain Symptom Manage 2003 ; 25, 5: 464-471.
1928 Revue Alvarez JC, De Mazancourt Ph, Chartier-Kastler E, Denys P.
Drug stability testing to support clinical feasibility investigations for intrathecal baclofen-clonidine admixture.
J Pain Symptom Manage 2004 ; 28, 3: 268-272.
1948 Revue Classen AM, Wimbish GH, Kupiec TC.
Stability of admixtures containing morphine sulfate, bupivacaine hydrochloride, and clonidine hydrochloride in an implantable infusion system.
J Pain Symptom Manage 2004 ; 28, 6: 603-611.
2018 Revue Veggeland T.
Visual compatibility of clonidine with selected drugs.
Am J Health-Syst Pharm 2005 ; 62: 1968-1969.
2184 Revue Vranken JH, van Kan HJM, ven der Vegt MH.
Stability and compatibility of a meperidine-clonidine mixture in portable pump reservoirs for the management of cancer pain syndromes.
J Pain Symptom Manage 2006 ; 32, 4: 297-299.
2248 Revue Shields D, Montenegro R.
Chemical stability of ziconotide-clonidine hydrochloride admixtures with and without morphine sulfate during simulated intrathecal administration.
Neuromodulation 2007 ; 10, 1: 6-11.
2305 Revue Bianchi F, Ginggen A, Tardy Y.
Stability and compatibility of drug mixtures in an implantable infusion system.
Anaesthesia 2008 63, 9: 972-978.
2317 Revue Hollenwaeger M, Borquin Challandes I, Fallab L.C, Schaad N, Zelger G.
Development and stability testing of a concentrated injectable clonidine solution for intrathecal analgesia.
EJHP Science 2009 ; 15, 1: 3-5.
3507 Laboratoire Chirocaine - Summary of Product Characteristics
AbbVie 2013
3705 Revue Knudsen L, Eisend S, Haake N, Kunze T.
Physicochemical compatibility of commonly used analgesics and sedatives in the intensive care medicine.
EJHP 2014 ;21:161-166
3728 Revue Correard F, Savry A, Gauthier-Villano L, Pisano P, Pourroy B.
Visual compatibility of defibrotide with selected drugs during simulated Y-site administration.
Am J Health-Syst Pharm 2014 ; 71: 1288-1291.
3823 Revue Juan E.P, Palau M.M, Cerd? S.A, Rubert M.A, Nicolau B.R.
Compatibilité physique de médicaments administrés dans l’unité de soins intensifs
Pharmactuel 2015 ; 48, 3 : 146-152.
4011 Revue Gersonde F, Eisend S, Haake N, Kunze T.
Physicochemical compatibility and emulsion stability of propofol with commonly used analgesics and sedatives in an intensive care unit.
EJHP 2016 2016;0:1-11
4130 Revue Koller AK, Krebs S, Dörje F.
Untersuchungen zur Kompatibilität von Clonidin mit häufig eingesetzen Arzneimittel auf Intensivstationen.
Pharmaceutics 2021 , 13, 21.
4538 Revue Campbell A, Petrovski M, Senarathna G, Mukadam ,Strunk T, Batty K.
Compatibility of pentoxifylline and parenteral medications.
Archives of Disease in Childhood 2020 ; 105: 395-397.
4643 Revue Catry E, Colsoul M-L, Closset M, Nyssen C, Hubert J, Soumoy L, Bihin B, Jamart J, Hecq J-D, Galanti L.
Evaluation of 30-day stability of morphine hydrochloride and clonidine at high and low concentrations in polypropylene syringes.
EJHP 2021
4698 Revue Ayari G, D'Huart E, Vigneron J, Demoré B.
Y-site compatibility of intravenous medications commonly used in intensive care units : laboratory tests on 75 mixtures involving nine main drugs.
Pharmaceutical Technology in Hospital Pharmacy 2022
4730 Revue Sorrieul J, Robert J, Vincent L, Andre M, Bourcier B, Bienfait F, Jubier Hamon S, Dupoiron D, Devys C.
Stability of Morphine Sulfate-Clonidine and Sufentanil-Clonidine Mixtures.
Neuromodulation 2022

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