Last update :
03/05/2024
Anticancer drug   Docetaxel  
Injection
Stability in solutions Stability of mixtures Factors which affect stability Compatibility Route of administration References Pdf
   Chemical structure  

Tradename   Tradename     

Trade names are indicative and excipients composition can be different depending on the country and manufacturers

Adenex Colombia
Asodocel Argentina
Axogen Chile
Bagotaxel Chile
Bendadocel Germany
Brecasta Chile
Celtere Peru
Daxotel Chile, Colombia, Egypt, Malaysia
Doce NC Germany
Docefrez India, United States of America
Docekebir Argentina
Docetax Iran, Venezuela
Docetaxin Germany
Docewin Morocco
Dolectran Argentina
Donataxel Argentina, Ecuador, Peru
Doxel Turkey, Venezuela
Doxetal Argentina
Doxitax Turkey
Oncodocel Colombia, Peru
Onkotaxel Austria, Colombia
Ribodocel Germany
Santax Turkey
Tadocel Turkey
Taxceus Great Britain
Taxotan Germany
Taxotere Argentina, Australia, Austria, Belgium, Canada, Chile, Colombia, Croatia, Denmark, Ecuador, Egypt, Finland, France, Germany, Great Britain, Greece, Hungary, Iceland, Iran, Italy, Japan, Luxembourg, Malaysia, Mexico, Morocco, Netherlands, New Zealand, Norway, Poland, Portugal, Romania, Saudi Arabia, Spain, Sweden, Switzerland, Thailand, Tunisia, Turkey, United Arab Emirates, United States of America, Venezuela
Texot Argentina
Tolnexa Romania
Zenotere India, Peru
References   Injection   References : Docetaxel  
Type Publication
140 Journal Pearson SD, Trissel LA.
Leaching of diethylhexyl phthalate from polyvinyl chloride containers by selected drugs and formulation components.
Am J Hosp Pharm 1993 ; 50: 1405-1409.
250 Journal Mazzo DJ, Nguyen-Huu JJ, Pagniez S, Denis P.
Compatibility of docetaxel and paclitaxel in intravenous solutions with polyvinyl chloride infusion materials.
Am J Health-Syst Pharm 1997 ; 54: 566-569.
251 Journal Trissel LA, Gilbert DL, Martinez JF.
Compatibility of doxorubicin hydrochloride liposome injection with selected other drugs during simulated Y-site administration.
Am J Health-Syst Pharm 1997 ; 54: 2708-2713.
1423 Journal Trissel LA, Martinez JF, Gilbert DL.
Compatibility of gemcitabine hyrochloride with 107 selected drugs during simulated Y-site injection.
J Am Pharm Assoc 1999 ; 39: 514-518.
1660 Journal Thiesen J, Krämer I.
Physico-chemical stability of docetaxel premix solution and docetaxel infusion solutions in PVC bags and polyolefine containers.
Pharm World Sci 1999 ; 21: 137-141.
1662 Journal Trissel LA, Saenz CA, Ingram DS, Ogundele AB.
Compatibility screening of oxaliplatin during simulated Y-site administration with other drugs.
J Oncol Pharm Practice 2002 ; 8: 33-37.
1754 Journal Trissel LA, Gilbert DL, Wolkin AC.
Compatibility of docetaxel with selected drugs during simulated Y-site administration.
Int J Pharm Compound 1999 ; 3: 241-244.
1940 Journal Xu QA, Trissel LA.
Stability of palonosetron hydrochloride with paclitaxel and docetaxel during simulated Y-site administration.
Am J Health-Syst Pharm 2004 ; 61: 1596-1598.
1953 Journal Trissel LA, Saenz CA, Ogundele AB, Ingram DS.
Physical compatibility of pemetrexed disodium with other drugs during simulated Y-site administration.
Am J Health-Syst Pharm 2004 ; 61: 2289-2293.
1982 Journal Trissel LA, Ogundele AB.
Compatibility of anidulafungin with other drugs during simulated Y-site administration.
Am J Health-Syst Pharm 2005 ; 62: 834-837.
2175 Journal Dalle M, Sautou-Miranda V, Balayssac D, Bourlon S, Bagel S, Chopineau J.
Peut-on conditionner les solutions de docétaxel dans des poches en PVC ?
J Pharm Clin 2006 ; 25, 3: 147-152.
2210 Journal Walker S.E, Charbonneau F, Law S.
Stability of Docetaxel Solution after Dilution in Ethanol and Storage in Vials and after Dilution in Normal Saline and Storage in Bags.
Can J Hosp Pharm 2007 ; 60, 4: 231-237.
2262 Journal Brammer MK, Chan P, Heatherly K, Trusley C, Kupiec TC, Trissel LA, Psathas PA, Gilmor T, Schaufelberger D.
Compatibility of doripenem with other drugs during simulated Y-site administratioN
Am J Health-Syst Pharm 2008 ; 65: 1261-1265.
2341 Poster Bourlon S, Sautou-Miranda V, Dalle M.
Release of di(2-ethylhexyl)phtalate from polyvinylchloride bags during docetaxel infusions
Poster ESCP Stockholm May 2005
3130 Manufacturer Docétaxel (Taxotere®) – Résumé des caractéristiques du produits
Sanofi Avantis France 2009
3163 Journal Acott SR, Hart M.
Physical and chemical stability of Taxotere 1-vial 20mg/mL infusion solution following refrigerated storage.
EJHP 2010 ; 16, 5: 26-28.
3195 Journal MacLeod S, Sewell G.
Physical and chemical stability of docetaxel infusions.
EJHP 2011 ; 17, 2: 39-43.
3215 Journal Hart MC, Ahmed W.
Taxotere 1-vial (docetaxel 20 mg/ml) physical and chemical stability over 28 days in infusion bags containing 0.9% saline solution and 5% glucose solution.
EJOP 2011 ; 5,1: 24-27.
3277 Journal Yang Z, Cameron S, Paul H.
Stability of Carboplatin, Paclitaxel, and Docetaxel with Acetyl-L-carnitine During Simulated Y-site Administration.
Int J Pharm Compound 2012 ; 16, 1 : 82-85.
3804 Journal Lazzarini R, Salvadori S, Trapella C, Guerrini R, Marzola E, Pasini G, Dalpiaz A.
Physicochemical stability of cabazitaxel and docetaxel solutions.
EJHP 2014 ;22:150-155.
3937 Journal Park K.H, Chung D.J.
Stability study of docetaxel solution (0.9% saline) using Non-PVC and PVC tubes for intravenous administration.
Biomat Res 2015 ; 19, 2

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