Dernière mise à jour :
18/04/2024
Anesthésique local   Bupivacaine hydrochloride  
Injectable
Stabilité des solutions Stabilité en mélange Facteur influençant la stabilité Compatibilités Voie d’administration Bibliographie Pdf
   Structure chimique  

Noms commerciaux   Noms commerciaux     

Les noms commerciaux sont donnés à titre indicatif et la composition en excipients peut être différente selon les pays et selon les laboratoires

Bicain Finlande
Bucain Allemagne, Autriche
Bucaine Arabie Saoudite
Bupi Alleman Allemagne
Bupinest Colombie, Equateur
Bupirop Equateur
Bupisen Italie
Bupivacain Allemagne
Bupivacaina Chili, Espagne
Bupivacaine Australie, Grande Bretagne, Irlande, Maroc, Tunisie
Bupivan Allemagne, Chili
Buvacaina Mexique
Buvasin Turquie
Carbostesin Allemagne, Autriche
Dolanaest Allemagne, Autriche
Duracaine Argentine
Inibsacain Espagne
Marcain Australie, Danemark, Egypte, Malaisie, Nouvelle Zélande
Marcaine Belgique
Sensorcaine Canada
Sinebupiv Equateur
Bibliographie   Injectable   Bibliographie : Bupivacaine hydrochloride  
Type Source
60 Revue Tu YH, Stiles ML, Allen LV Jr.
Stability of fentanyl citrate and bupivacaine hydrochloride in portable pump reservoirs.
Am J Hosp Pharm 1990 ; 47: 2037-2040.
217 Revue Allen LV, Stiles ML, Wang DP, Tu YH.
Stability of bupivacaine hydrochloride, epinephrine hydrochloride, and fentanyl citrate in portable infusion-pump reservoirs.
Am J Hosp Pharm 1993 ; 50: 714-715.
220 Revue Johnson CE, Christen C, Perez MM, Ma M.
Compatibility of bupivacaine hydrochloride and morphine sulfate.
Am J Health-Syst Pharm 1997 ; 54: 61-64.
221 Revue Neels JT.
Compatibility of bupivacaine hydrochloride with hydromorphone hydrochloride or morphine sulfate.
Am J Hosp Pharm 1992 ; 49: 2149.
293 Revue Jones JW, Davis AT.
Stability of bupivacaine hydrochloride in polypropylene syringes.
Am J Hosp Pharm 1993 ; 50: 2364-2365.
306 Revue Christen C, Johnson CE, Walters JR.
Stability of bupivacaine hydrochloride and hydromorphone hydrochloride during simulated epidural coadministration.
Am J Health-Syst Pharm 1996 ; 53: 170-173.
346 Revue Wulf H, Gleim M, Mignat C.
The stability of mixtures of morphine hydrochloride, bupivacaine hydrochloride, and clonidine hydrochloride in portable pump reservoirs for the management of chronic pain syndromes.
J Pain Symptom Manage 1994 ; 9: 308-311.
507 Revue Dawson PJ, Bjorksten AR, Duncan IP, Barnes RK, Beemer GH.
Stability of fentanyl, bupivacaine and adrenaline solutions for extradural infusion.
Br J Anaesth 1992 ; 68: 414-417.
510 Revue Roos PJ, Glerum JH, Schroeders MJH.
Effect of glucose 5% solution and bupivacaine hydrochloride on absorption of sufentanil citrate in a portable pump reservoir during storage and simulated infusion by an epidural catheter.
Pharm World Sci 1993 ; 15: 269-275.
512 Revue Barnes AR, Nash S.
Stability of bupivacaine hydrochloride with diamorphine hydrochloride in an epidural infusion.
Pharm World Sci 1995 ; 17: 87-92.
529 Revue Van Asten P, Glerum JH, Spaanderman ER, Van Niekerk J, Van Dijk A.
Compatibility of bupivacaine and iohexol in two mixtures for paediatric regional anaesthesia.
Pharm Weekbl [Sci] 1991 ; 13: 254-256.
1276 Revue Shiffman E, Walker SE, Yoon T, Yeung M.
Stability and compatibility of morphine with bupivacaine.
Can J Hosp Pharm 1998 ; 51: 110-116.
1292 Revue Grassby PF, Roberts DE.
Stability of epidural opiate solutions in 0.9 per cent sodium chloride infusion bags.
Int J Pharm Pract 1995 ; 3: 174-177.
1491 Revue Brouwers JRBJ, van Doorne H, Meevis RF, Boersma FP.
Stability of sufentanil citrate and sufentanil citrate/bupivacaine mixture in portable infusion pump reservoirs.
Eur Hosp Pharm 1995 ; 1: 12-14.
1707 Revue Trissel LA, Xu QA, Pham L.
Physical and chemical stability of low and high concentrations of morphine sulfate with bupivacaine hydrochloride packaged in plastic syringes.
Int J Pharm Compound 2002 ; 6: 70-73.
1723 Revue Sattler A, Jage J, Krämer I.
Physico-chemical stability of infusion solutions for epidural administration containing fentanyl and bupivacaine or lidocaine.
Pharmazie 1998 ; 53: 386-391.
1875 Revue Kjonniksen I, Brustugun J, Breivik H, Anderssen E, Klem W.
Stability of an epidural analgesic solution containing adrenaline, bupivacaine and fentanyl.
Acta Anaesthesiol Scand 2000 ; 44: 864-867.
1879 Revue Hildebrand KR, Elsberry DE, Deer TR.
Stability, compatibility, and safety of intrathecal bupivacaine administered via an implantable delivery system.
Clin J Pain 2001 : 17: 239-244.
1885 Revue Essink-Tjebbes CM, Burger DM, Beelen, Wuis EW, Heckster YA.
Long-term stability of morphine and bupivacaine mixture for spinal use.
Pharm World Sci 1999 ; 21: 144-146.
1909 Revue Farhang-Asnefi S, Barre J, Callaert S, Boutros A, Causse R, Thebault A.
Compatibilité et stabilité du mélange bupivacaïne-sufentanil en poche.
J Pharm Clin 2000 ; 19: 248-251.
1931 Revue Donnely RF.
Physical compatibility and chemical stability of bupivacaine and hydromorphone in polypropylene syringes.
Can J Hosp Pharm 2004 ; 4: 230-235.
1948 Revue Classen AM, Wimbish GH, Kupiec TC.
Stability of admixtures containing morphine sulfate, bupivacaine hydrochloride, and clonidine hydrochloride in an implantable infusion system.
J Pain Symptom Manage 2004 ; 28, 6: 603-611.
2083 Revue La Forgia SP, Sharley NA, Burgess NG, Doecke CJ.
Stability and compatibility of morphine, midazolam and bupivacaine combinaisons for iontravenous infusion.
J Pharm Pract and Res 2002 ; 32: 65-68.
2252 Revue Shields D, Montenegro R, Aclan J.
Chemical stability of admixture combining ziconotide and bupivacaine during simulated intrathecal administration.
Neuromodulation 2007 ; 10, 1: 1-5.
2305 Revue Bianchi F, Ginggen A, Tardy Y.
Stability and compatibility of drug mixtures in an implantable infusion system.
Anaesthesia 2008 63, 9: 972-978.
2306 Revue Priston M.J, Hughes J.M, Santillo M, Christie I.W.
Stability of an epidural analgesic admixture containing epinephrine, fentanyl and bupivacaine.
Anaesthesia 2004 ; 59, 10: 979-983.
2307 Revue Kreeger L, Cowin P, Noble-Gresty J, Naysmith A.
Epidural diamorphine and bupivacaine stability study.
Palliative Med 1995 ; 9, 4: 315-318.
2308 Revue Hudson S.J, Jones M.F, Nolan S, Ellis H, Duncombe R, Alexander-Williams J.M.
Stability of premixed syringes of diamorphine and hyperbaric bupivacaine.
Int J Obstet Anesth 2005 ; 14, 4: 284-287.
2319 Revue Janssen K, Wisselo R, Geerlings C, Schouten J.P.
Chemical stability of a solution of bupivacaine hydrochloride 0.125% and sufentanil citrate 0.5 µg/ml for filling syringes using a repeater pump.
EJHP Science 2009 ; 15, 1: 11-14.
3131 Revue Donnely RF, Wong K, Spencer J.
Physical compatibility of high-concentration bupivacaine with hydromorphone, morphine and fentanyl.
Can J Hosp Pharm 2010 ; 63, 2: 154-155.
3184 Laboratoire
Hyaluronidase (Hyalase®) - Summary of Product characteristics.
CP Pharmaceuticals 2005
3296 Revue Salmeron-Garcia A, Navas N, Martin A, Roman E, Cabeza J, Capitan-Vallvey L.F
Determination of Tramadol, Metamizole, Ropivacaine, and Bupivacaine in Analgesic Mixture Samples by HPLC with DAD Detection.
J Chromatographic Sci 2009 ; 47: 1-7.
3372 Revue Hanci V, Ali Kiraz H, Ömür D, Ekin S, Uyan B, Yurtlu B.S.
Precipitation in Gallipoli: Sugammadex / Amiodarone & Sugammadex / Dobutamine & Sugammadex / Protamine.
Rev Bras Anestesiol 2013 ; 63, 1: 163-166.
3964 Revue Audet M.A, Forest E, Friciu M, Forest J.M, Leclair G.
Compatibilité du citrate de caféine injectable avec plusieurs autres médicaments.
Pharmactuel 2017 ; 50,1 : 27-33.
4200 Revue Macorigh C, Guibbert V, Casanova M, Haenni C.
Stability study of hydromorphone and bupivacaine mixture by HPLC-UV.
EJHP 2018
4319 Revue Lessard J-J, Caron E, Schérer H, Forest J-M, Leclair G.
Compatibility of Y-site Injection of Meropenem Trihydrate With 101 Other Injectable Drugs.
Hosp Pharm 2020 ; 55, 5: 332-337.
4603 Revue Vallée M, Barthélémy I, Friciu M, Pelletier E, Forest J.M, Benoit F, Leclair G.
Compatibility of Lactated Ringer’s Injection With 94 Selected Intravenous Drugs During Simulated Y-site Administration.
Hosp Pharm 2021 ; 56, 4: 228-234.
4746 Poster Shead K, Derrick H, Lyons D, Law S, Ma N.H.
Stability and Compatibility of Bupivacaine and Hydromorphone in PVC and non-DEHP bags for 30 days at 4°C and 25°C.
2023

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