Last update :
15/04/2024
References   References 4746  
Type : Poster
Web link : http://metrodis.org/SB PPC2015.html
Icone.pdf
886Ko

Research teams : Toronto - Sunnybrook Health Sciences Center
Authors : Shead K, Derrick H, Lyons D, Law S, Ma N.H.
Title : Stability and Compatibility of Bupivacaine and Hydromorphone in PVC and non-DEHP bags for 30 days at 4°C and 25°C.
Reference : 2023

Level of Evidence : 
Level of evidence A
Physical stability : 
Chemical stability : 
High Performance Liquid Chromatography - ultraviolet detector (HPLC-UV)
Stability defined as 95% of the initial concentration
Other methods : 
Comments : 

List of drugs
InjectionBupivacaine hydrochloride Local anesthetic
InjectionHydromorphone hydrochloride Analgesic
Stability of mixtures
Polyvinyl chloride Sodium chloride 0,9% 25°C Not specified
Injection Hydromorphone hydrochloride 0.0015 mg/ml
Injection Bupivacaine hydrochloride 0.5 mg/ml
30 Day
Polyvinyl chloride Sodium chloride 0,9% 25°C Not specified
Injection Bupivacaine hydrochloride 0.5 mg/ml
Injection Hydromorphone hydrochloride 0.03 mg/ml
30 Day
Polyvinyl chloride Sodium chloride 0,9% 25°C Not specified
Injection Bupivacaine hydrochloride 2.5 mg/ml
Injection Hydromorphone hydrochloride 0.03 mg/ml
30 Day
Polyvinyl chloride Sodium chloride 0,9% 25°C Not specified
Injection Bupivacaine hydrochloride 2.5 mg/ml
Injection Hydromorphone hydrochloride 0.0015 mg/ml
30 Day
Polyvinyl chloride Sodium chloride 0,9% 4°C Not specified
Injection Hydromorphone hydrochloride 0.0015 mg/ml
Injection Bupivacaine hydrochloride 0.5 mg/ml
30 Day
Polyvinyl chloride Sodium chloride 0,9% 4°C Not specified
Injection Bupivacaine hydrochloride 0.5 mg/ml
Injection Hydromorphone hydrochloride 0.03 mg/ml
30 Day
Polyvinyl chloride Sodium chloride 0,9% 4°C Not specified
Injection Bupivacaine hydrochloride 2.5 mg/ml
Injection Hydromorphone hydrochloride 0.03 mg/ml
30 Day
Polyvinyl chloride Sodium chloride 0,9% 4°C Not specified
Injection Bupivacaine hydrochloride 2.5 mg/ml
Injection Hydromorphone hydrochloride 0.0015 mg/ml
30 Day
Polyolefine Sodium chloride 0,9% 25°C Not specified
Injection Hydromorphone hydrochloride 0.0015 mg/ml
Injection Bupivacaine hydrochloride 0.5 mg/ml
30 Day
Polyolefine Sodium chloride 0,9% 25°C Not specified
Injection Bupivacaine hydrochloride 0.5 mg/ml
Injection Hydromorphone hydrochloride 0.03 mg/ml
30 Day
Polyolefine Sodium chloride 0,9% 25°C Not specified
Injection Bupivacaine hydrochloride 2.5 mg/ml
Injection Hydromorphone hydrochloride 0.03 mg/ml
30 Day
Polyolefine Sodium chloride 0,9% 25°C Not specified
Injection Bupivacaine hydrochloride 2.5 mg/ml
Injection Hydromorphone hydrochloride 0.0015 mg/ml
30 Day
Polyolefine Sodium chloride 0,9% 4°C Not specified
Injection Hydromorphone hydrochloride 0.0015 mg/ml
Injection Bupivacaine hydrochloride 0.5 mg/ml
30 Day
Polyolefine Sodium chloride 0,9% 4°C Not specified
Injection Bupivacaine hydrochloride 0.5 mg/ml
Injection Hydromorphone hydrochloride 0.03 mg/ml
30 Day
Polyolefine Sodium chloride 0,9% 4°C Not specified
Injection Bupivacaine hydrochloride 2.5 mg/ml
Injection Hydromorphone hydrochloride 0.03 mg/ml
30 Day
Polyolefine Sodium chloride 0,9% 4°C Not specified
Injection Bupivacaine hydrochloride 2.5 mg/ml
Injection Hydromorphone hydrochloride 0.0015 mg/ml
30 Day

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