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References   References 4714  
Type : Poster
Icone.pdf
629Ko
Research teams : Créteil - Henri Mondor University Hospital, Department of Pharmacy
Authors : Vieillard V, Paul M
Title : Etude de stabilité d'un biosimilaire du Bevacizumab dans les flacons et après dilution dans du NaCl 0.9% en poche de polyoléfine.
Reference : GERPAC Congrès - octobre 2022 2022
Level of Evidence : 
Level of evidence A+
Physical stability : 
Turbidimetry Protein: Size Exclusion Chromatography Protein: Dynamic Light Scattering 
Chemical stability : 
Protein: ionic chromatography
Other methods : 
PH measurement Measurement of osmolality 
Comments : 
List of drugs
InjectionBevacizumab Anticancer drug
Stability in solutions Glass None 25 mg/ml 20-25°C Protect from light
15 Day
Biosimilar
Stability in solutions Partially used vials None 25 mg/ml 4°C Protect from light
60 Day
Biosimilar
Stability in solutions Polyolefine Sodium chloride 0,9% 1,4 & 16,5 mg/ml 25°C Not specified
3 Day
Biosimilar
Stability in solutions Polyolefine Sodium chloride 0,9% 1,4 & 16,5 mg/ml 4°C Protect from light
90 Day
Biosimilar
  Mentions Légales