Last update :
28/04/2024
References   References 226  
Type : Journal

Research teams : Toronto - Sunnybrook Health Sciences Center
Authors : Walker SE, DeAngelis C, Iazzetta J.
Title : Stability and compatibility of combinations of hydromorphone and a second drug.
Reference : Can J Hosp Pharm ; 44: 289-295. 1991

Level of Evidence : 
Physical stability : 
Chemical stability : 
Other methods : 
Comments : 

List of drugs
InjectionAmpicillin sodium Antibiotic
Compatible 20 & 250 mg/ml + InjectionHydromorphone hydrochloride 2 >> 40 mg/ml + Glucose 5%
InjectionCefazolin sodium Antibiotic
Incompatible >200 mg/ml + InjectionHydromorphone hydrochloride 2 >> 40 mg/ml + Glucose 5%
Compatible 20 mg/ml + InjectionHydromorphone hydrochloride 2 >> 40 mg/ml + Glucose 5%
InjectionCeftazidime Antibiotic
Compatible 40 & 180 mg/ml + InjectionHydromorphone hydrochloride 2 >> 40 mg/ml + Glucose 5%
InjectionCloxacillin sodium Antibiotic
Incompatible 40 & 250 mg/ml + InjectionHydromorphone hydrochloride 2 >> 40 mg/ml + Glucose 5%
InjectionDiazepam Anxiolytic
Incompatible 5 mg/ml + InjectionHydromorphone hydrochloride 2 >> 40 mg/ml + Glucose 5%
InjectionHydromorphone hydrochloride Analgesic
Compatible 2 >> 40 mg/ml + InjectionAmpicillin sodium 20 & 250 mg/ml + Glucose 5%
Incompatible 2 >> 40 mg/ml + InjectionCefazolin sodium >200 mg/ml + Glucose 5%
Compatible 2 >> 40 mg/ml + InjectionCefazolin sodium 20 mg/ml + Glucose 5%
Compatible 2 >> 40 mg/ml + InjectionCeftazidime 40 & 180 mg/ml + Glucose 5%
Incompatible 2 >> 40 mg/ml + InjectionCloxacillin sodium 40 & 250 mg/ml + Glucose 5%
Incompatible 2 >> 40 mg/ml + InjectionDiazepam 5 mg/ml + Glucose 5%
Incompatible 2 >> 40 mg/ml + InjectionPhenobarbital sodium 120 mg/ml + Glucose 5%
Incompatible 2 >> 40 mg/ml + InjectionPhenytoin sodium 50 mg/ml + Glucose 5%
InjectionPhenobarbital sodium Antiepileptic
Incompatible 120 mg/ml + InjectionHydromorphone hydrochloride 2 >> 40 mg/ml + Glucose 5%
InjectionPhenytoin sodium Antiepileptic
Incompatible 50 mg/ml + InjectionHydromorphone hydrochloride 2 >> 40 mg/ml + Glucose 5%

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