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Anticancer drug   Cytarabine  
Injection
Stability in solutions Stability of mixtures Factors which affect stability Compatibility Route of administration References Pdf
   Chemical structure  

Tradename   Tradename     

Trade names are indicative and excipients composition can be different depending on the country and manufacturers
Alexan Austria, Chile, Colombia, Egypt, Germany, Hungary, Luxembourg, Netherlands, Republic of South Africa, Russian, Saudi Arabia, Thailand, Turkey, United Arab Emirates
Alexane Iran
Ara Cell Germany, Portugal
Arabine Denmark, Finland, Iceland, Sweden
Aracytin Brazil, Chile, Colombia, Egypt, Greece, Italy
Aracytine Colombia, France, Morocco
Cancyt India
Citab Brazil
Citarabina Argentina, Chile, Colombia, Ecuador, Italy, Mexico, Spain
Cylocide Japan
Cytaban Colombia
Cytaloxan Portugal
Cytarabine Australia, Belgium, Canada, Denmark, Egypt, Finland, Great Britain, Ireland, Malaysia, New Zealand, United Arab Emirates, United States of America
Cytarax Brazil, Mexico
Cytonal Turkey
Cytosafe Great Britain
Cytosar Austria, Belgium, Canada, Croatia, Denmark, Hungary, Iran, Ireland, Luxembourg, Malaysia, Netherlands, Norway, Poland, Portugal, Republic of South Africa, Saudi Arabia, Switzerland, United Arab Emirates, Venezuela
Ifarab Mexico
Laracit Chile, Colombia, Mexico
Medsara Mexico
Novutrax Colombia, Mexico
Oncorab Venezuela
Tabine Ecuador
Udicil Germany
Zuphacit Mexico
Stability of mixtures   Injection   Stability of mixtures : Cytarabine     
Container Solvent Concentration Compound Temperature Storage Duration of stability References
Glass Water for Injection 1 mg/ml
Injection   Cytarabine   
Injection   Granisetron hydrochloride 0,5 mg/ml
20°C-23°C
4 Hour
Light 57
Level of evidence A+
Glass Glucose 5% 0,2 & 1 mg/ml
Injection   Cytarabine   
Injection   Sodium bicarbonate 50 mg/ml
22°C
7 Day
Not specified 850
Level of evidence B
Glass Glucose 5% 0,2 & 1 mg/ml
Injection   Cytarabine   
Injection   Sodium bicarbonate 50 mg/ml
8°C
7 Day
Protect from light 850
Level of evidence B
Glass Elliott’s B solution 0,442 mg/ml
Injection   Cytarabine   
Injection   Methotrexate sodium 0,0279 mg/ml
23°C
48 Hour
Not specified 1661
Level of evidence B
Glass Elliott’s B solution 0,484 mg/ml
Injection   Cytarabine   
Injection   Methotrexate sodium 0,0314 mg/ml
Injection   Hydrocortisone sodium succinate 0,478 mg/ml
23°C
48 Hour
Not specified 1661
Level of evidence B
Glass Elliott’s B solution 0,477 mg/ml
Injection   Cytarabine   
Injection   Methotrexate sodium 0,0581 mg/ml
Injection   Hydrocortisone sodium succinate 0,467 mg/ml
23°C
48 Hour
Not specified 1661
Level of evidence B
Glass Elliott’s B solution 0,433 mg/ml
Injection   Cytarabine   
Injection   Methotrexate sodium 0,0542 mg/ml
23°C
48 Hour
Not specified 1661
Level of evidence B
Glass Elliott’s B solution 0,479 mg/ml
Injection   Cytarabine   
Injection   Methotrexate sodium 0,0721 mg/ml
Injection   Hydrocortisone sodium succinate 0,489 mg/ml
23°C
48 Hour
Not specified 1661
Level of evidence B
Glass Elliott’s B solution 0,431 mg/ml
Injection   Cytarabine   
Injection   Methotrexate sodium 0,0649 mg/ml
23°C
48 Hour
Not specified 1661
Level of evidence B
Glass Elliott’s B solution 0,484 mg/ml
Injection   Cytarabine   
Injection   Methotrexate sodium 0,0314 mg/ml
Injection   Hydrocortisone sodium succinate 0,478 mg/ml
4°C
48 Hour
Not specified 1661
Level of evidence B
Glass Elliott’s B solution 0,442 mg/ml
Injection   Cytarabine   
Injection   Methotrexate sodium 0,0279 mg/ml
4°C
48 Hour
Not specified 1661
Level of evidence B
Glass Elliott’s B solution 0,477 mg/ml
Injection   Cytarabine   
Injection   Methotrexate sodium 0,0581 mg/ml
Injection   Hydrocortisone sodium succinate 0,467 mg/ml
4°C
48 Hour
Not specified 1661
Level of evidence B
Glass Elliott’s B solution 0,433 mg/ml
Injection   Cytarabine   
Injection   Methotrexate sodium 0,0542 mg/ml
4°C
48 Hour
Not specified 1661
Level of evidence B
Glass Elliott’s B solution 0,479 mg/ml
Injection   Cytarabine   
Injection   Methotrexate sodium 0,0721 mg/ml
Injection   Hydrocortisone sodium succinate 0,489 mg/ml
4°C
48 Hour
Not specified 1661
Level of evidence B
Glass Elliott’s B solution 0,431 mg/ml
Injection   Cytarabine   
Injection   Methotrexate sodium 0,0649 mg/ml
4°C
48 Hour
Not specified 1661
Level of evidence B
Polyvinyl chloride Glucose 5% 0,2 & 40 mg/ml
Injection   Cytarabine   
Injection   Ondansetron hydrochloride 0,03 & 0,3 mg/ml
21°C-23°C
48 Hour
Light 184
Level of evidence C+
Polyvinyl chloride Glucose 5% 0,2 & 1 mg/ml
Injection   Cytarabine   
Injection   Sodium bicarbonate 50 mg/ml
22°C
7 Day
Not specified 850
Level of evidence B
Polyvinyl chloride Glucose 5% 0,2 & 1 mg/ml
Injection   Cytarabine   
Injection   Sodium bicarbonate 50 mg/ml
8°C
7 Day
Protect from light 850
Level of evidence B
Polyvinyl chloride NaCl 0,45% Glucose 5% 0,26 mg/ml
Injection   Cytarabine   
Injection   Daunorubicin hydrochloride 0,03 mg/ml
Injection   Etoposide 0,4 mg/ml
20°C
72 Hour
Light 643
Level of evidence D
Polypropylene Glucose 5% 0,157 mg/ml
Injection   Cytarabine   
Injection   Etoposide 0,157 mg/ml
Injection   Daunorubicin hydrochloride 0,0157 mg/ml
25°C
48 Hour
With or without light 152
Joker
Polypropylene Glucose 5% 0,157 mg/ml
Injection   Cytarabine   
Injection   Etoposide 0,157 mg/ml
Injection   Daunorubicin hydrochloride 0,0157 mg/ml
4°C
48 Hour
Protect from light 152
Joker
Polypropylen Syringe NaCl 0,9% or Glucose 5% 4,1 mg/ml
Injection   Cytarabine   
Injection   Hydrocortisone sodium succinate 2 mg/ml
Injection   Methotrexate sodium 1 mg/ml
25°C
24 Hour
Not specified 1028
Level of evidence A
Polypropylen Syringe Ringer’s lactate solution 4,1 mg/ml
Injection   Cytarabine   
Injection   Hydrocortisone sodium succinate 2 mg/ml
Injection   Methotrexate sodium 1 mg/ml
25°C
24 Hour
Not specified 1028
Level of evidence A
Polypropylen Syringe Elliott’s B solution 4,1 mg/ml
Injection   Cytarabine   
Injection   Hydrocortisone sodium succinate 2 mg/ml
Injection   Methotrexate sodium 1 mg/ml
25°C
24 Hour
Not specified 1028
Level of evidence A
Polypropylen Syringe None 3,85 mg/ml
Injection   Cytarabine   
Injection   Methylprednisolone sodium succinate 0,51 mg/ml
Injection   Methotrexate sodium 1,54 mg/ml
5°C
12 Hour
Protect from light 3275
Level of evidence A
  Mentions Légales