Last update :
17/04/2024
References   References 585  
Type : Journal

Research teams : Houston - University of Houston, College of Pharmacy
Authors : Das Gupta V, Bethea C, Dela Torre M.
Title : Chemical stabilities of cefaperazone sodium and ceftazidime in 5% dextrose and 0.9% sodium chloride injections.
Reference : J Clin Pharm Ther ; 13: 199-205. 1988

Level of Evidence : 
Level of evidence D
Physical stability : 
Visual examination 
Chemical stability : 
High Performance Liquid Chromatography - ultraviolet detector (HPLC-UV)
Stability defined as 90% of the initial concentration
Other methods : 
PH measurement 
Comments : 
No comments for the degradation products

List of drugs
InjectionCefoperazone sodium Antibiotic
Stability in solutions Glass NaCl 0,9% or Glucose 5% 40 mg/ml -10°C Protect from light
96 Day
Stability in solutions Glass NaCl 0,9% or Glucose 5% 40 mg/ml 25°C Not specified
8 Day
Stability in solutions Glass NaCl 0,9% or Glucose 5% 40 mg/ml 5°C Protect from light
80 Day
InjectionCeftazidime Antibiotic
Factors which affect stability Solvent Sodium chloride 0,9% Induces Enhanced stability
Stability in solutions Polyvinyl chloride NaCl 0,9% or Glucose 5% 40 mg/ml -10°C Protect from light
90 Day

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