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Anticancer drug   Gemcitabine hydrochloride  
Injection
Stability in solutions Stability of mixtures Factors which affect stability Compatibility Route of administration References Pdf
   Chemical structure  

Tradename   Tradename     

Trade names are indicative and excipients composition can be different depending on the country and manufacturers
Accogem Mexico
Antoril Argentina
Axigem Germany
Bendacitabin Germany
Binoptos Mexico
Celzar Peru
Dercin Romania
Dhacibine Malaysia
Emcitab Colombia
Eriogem Argentina, Ecuador
Fotinex Argentina, Peru
Gebina Argentina
Gebitan Colombia
Gembio Argentina, Chile, Ecuador
Gemcimira Chile, Peru
Gemcit Portugal
Gemcitabin Germany
Gemcitac Chile
Gemko Turkey
Gemsibin Turkey
Gemsol Austria
Gemtero Chile, Peru
Gemzar Australia, Austria, Belgium, Brazil, Canada, Chile, Colombia, Croatia, Denmark, Ecuador, Egypt, Finland, France, Germany, Great Britain, Greece, Hungary, Iceland, Iran, Ireland, Italy, Luxembourg, Malaysia, Mexico, Morocco, Netherlands, New Zealand, Norway, Poland, Portugal, Republic of South Africa, Romania, Slovenia, Spain, Sweden, Switzerland, Thailand, Tunisia, Turkey, United Arab Emirates, United States of America, Venezuela
Gentabin Colombia
Haxanit Argentina, Peru
Lenfotabin Mexico
Stability in solutions   Injection   Stability in solutions : Gemcitabine hydrochloride     
Container Solvent Concentration Temperature Storage Duration of stability References
Glass Water for Injection 38 mg/ml 23°C With or without light
35 Day
1422
Level of evidence A+
Glass Sodium chloride 0,9% 0,1 & 25 mg/ml 2-8°C Protect from light
35 Day
2344
Manufacturer's stability data
Glass Sodium chloride 0,9% 0,1 & 25 (Ebegemcit® Lyo) mg/ml 20-25°C
14 Day
2344
Manufacturer's stability data
Glass Sodium chloride 0,9% 38 mg/ml 23°C With or without light
35 Day
1422
Level of evidence A+
Glass Sodium chloride 0,9% 40 mg/ml 25°C With or without light
27 Day
1663
Level of evidence A
Glass Sodium chloride 0,9% 5,12 mg/ml 23°C Protect from light
48 Hour
1501
Level of evidence A
Glass Sodium chloride 0,9% 7,5 & 25 mg/ml 25°C With or without light
27 Day
1663
Level of evidence A
Glass Glucose 5% 0,1 & 25 mg/ml 2-8°C Protect from light
35 Day
2344
Manufacturer's stability data
Glass Glucose 5% 0,1 & 25 (Ebegemcit® Lyo) mg/ml 20-25°C
14 Day
2344
Manufacturer's stability data
Polyvinyl chloride NaCl 0,9% or Glucose 5% 0,1 & 10 mg/ml 23°C With or without light
35 Day
1422
Level of evidence A+
Polyvinyl chloride NaCl 0,9% or Glucose 5% 0,1 & 10 mg/ml 4°C Protect from light
35 Day
1422
Level of evidence A+
Polyvinyl chloride NaCl 0,9% or Glucose 5% 0,1 & 10 & 38 mg/ml 32°C Protect from light
7 Day
1422
Level of evidence A+
Polyvinyl chloride Sodium chloride 0,9% 0,1 & 25 mg/ml 2-8°C Protect from light
35 Day
2344
Manufacturer's stability data
Polyvinyl chloride Sodium chloride 0,9% 0,1 & 25 (Ebegemcit® Lyo) mg/ml 20-25°C
14 Day
2344
Manufacturer's stability data
Polyvinyl chloride Sodium chloride 0,9% 2 mg/ml 25°C Light
28 Day
3496
Manufacturer's stability data
Polyvinyl chloride Sodium chloride 0,9% 2 mg/ml 5°C Protect from light
28 Day
3496
Manufacturer's stability data
Polyvinyl chloride Sodium chloride 0,9% 5,12 mg/ml 23°C Protect from light
48 Hour
1501
Level of evidence A
Polyvinyl chloride Sodium chloride 0,9% 5.2 mg/ml 25°C Light
28 Day
3496
Manufacturer's stability data
Polyvinyl chloride Sodium chloride 0,9% 5.2 mg/ml 5°C Protect from light
28 Day
3496
Manufacturer's stability data
Polyvinyl chloride Sodium chloride 0,9% 7,5 & 25 mg/ml 25°C With or without light
27 Day
1663
Level of evidence A
Polyvinyl chloride Glucose 5% 0,1 & 25 mg/ml 2-8°C Protect from light
35 Day
2344
Manufacturer's stability data
Polyvinyl chloride Glucose 5% 0,1 & 25 (Ebegemcit® Lyo) mg/ml 20-25°C
14 Day
2344
Manufacturer's stability data
Polyethylene Sodium chloride 0,9% 0,1 & 25 mg/ml 2-8°C Protect from light
35 Day
2344
Manufacturer's stability data
Polyethylene Sodium chloride 0,9% 0,1 & 25 (Ebegemcit® Lyo) mg/ml 20-25°C
14 Day
2344
Manufacturer's stability data
Polyethylene Sodium chloride 0,9% 2 mg/ml 25°C Light
28 Day
3496
Manufacturer's stability data
Polyethylene Sodium chloride 0,9% 2 mg/ml 5°C Protect from light
28 Day
3496
Manufacturer's stability data
Polyethylene Sodium chloride 0,9% 5,12 mg/ml 22°C Not specified
48 Hour
1520
Manufacturer's stability data
Polyethylene Sodium chloride 0,9% 5,12 mg/ml 23°C Protect from light
48 Hour
1501
Level of evidence A
Polyethylene Sodium chloride 0,9% 5.2 mg/ml 25°C Light
28 Day
3496
Manufacturer's stability data
Polyethylene Sodium chloride 0,9% 5.2 mg/ml 5°C Protect from light
28 Day
3496
Manufacturer's stability data
Polyethylene Glucose 5% 0,1 & 25 mg/ml 2-8°C Protect from light
35 Day
2344
Manufacturer's stability data
Polyethylene Glucose 5% 0,1 & 25 (Ebegemcit® Lyo) mg/ml 20-25°C Light
14 Day
2344
Manufacturer's stability data
Polypropylene Sodium chloride 0,9% 0,1 & 25 mg/ml 2-8°C Protect from light
35 Day
2344
Manufacturer's stability data
Polypropylene Sodium chloride 0,9% 0,1 & 25 (Ebegemcit® Lyo) mg/ml 20-25°C Light
14 Day
2344
Manufacturer's stability data
Polypropylene Glucose 5% 0,1 & 25 mg/ml 2-8°C Protect from light
35 Day
2344
Manufacturer's stability data
Polypropylene Glucose 5% 0,1 & 25 (Ebegemcit® Lyo) mg/ml 20-25°C
14 Day
2344
Manufacturer's stability data
Polyolefine Sodium chloride 0,9% 5,5>>6,6 mg/ml 2-8°C Not specified
49 Day
4736
Level of evidence B+
Polyolefine Sodium chloride 0,9% 5,5>>6,6 mg/ml 21-25°C Not specified
49 Day
4736
Level of evidence B+
Polyolefine Sodium chloride 0,9% 9 mg/ml 2-8°C Protect from light
84 Day
3670
Level of evidence A+
Polypropylen Syringe Sodium chloride 0,9% 38 mg/ml 23°C With or without light
35 Day
1422
Level of evidence A+
  Mentions Légales