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Analgesic   Diamorphine hydrochloride  
Injection
Stability in solutions Stability of mixtures Factors which affect stability Compatibility Route of administration References Pdf
   Chemical structure  

Tradename   Tradename     

Trade names are indicative and excipients composition can be different depending on the country and manufacturers
Diamorphine hydrochloride for injection Great Britain
Diaphin Switzerland
Stability of mixtures   Injection   Stability of mixtures : Diamorphine hydrochloride     
Container Solvent Concentration Compound Temperature Storage Duration of stability References
Polyvinyl chloride Sodium chloride 0,9% 0,02 mg/ml
Injection   Diamorphine hydrochloride   
Injection   Bupivacaine hydrochloride 1,5 mg/ml
-18C
180 Day
Protect from light 512
Level of evidence A
Polyvinyl chloride Sodium chloride 0,9% 0,125 mg/ml
Injection   Diamorphine hydrochloride   
Injection   Bupivacaine hydrochloride 1,25 mg/ml
25°C
28 Day
Light 1292
Level of evidence B
Polyvinyl chloride Sodium chloride 0,9% 0,02 mg/ml
Injection   Diamorphine hydrochloride   
Injection   Bupivacaine hydrochloride 1,5 mg/ml
25°C
24 Hour
Light 512
Level of evidence A
Polyvinyl chloride Sodium chloride 0,9% 0,02 mg/ml
Injection   Diamorphine hydrochloride   
Injection   Bupivacaine hydrochloride 1,5 mg/ml
7°C
14 Day
Protect from light 512
Level of evidence A
Polyvinyl chloride None 0,5 >> 10 mg/ml
Injection   Diamorphine hydrochloride   
Injection   Bupivacaine hydrochloride 2,5 et 5 mg/ml
25°C
8 Day
Protect from light 2307
Level of evidence B
Polypropylene None 0,045 mg/ml
Injection   Diamorphine hydrochloride   
Injection   Ropivacain hydrochloride 1 mg/ml
21°C
16 Day
Not specified 2051
Level of evidence D
Polypropylene None 0,045 mg/ml
Injection   Diamorphine hydrochloride   
Injection   Ropivacain hydrochloride 1 mg/ml
40°C
6 Day
Not specified 2051
Level of evidence D
Polypropylene None 0,045 mg/ml
Injection   Diamorphine hydrochloride   
Injection   Ropivacain hydrochloride 1 mg/ml
4°C
30 Day
Not specified 2051
Level of evidence D
Polypropylen Syringe Water for Injection 20 mg/ml
Injection   Diamorphine hydrochloride   
Injection   Cyclizine lactate 6,7 mg/ml
18-22°C
10 Day
Light 1886
Level of evidence D
Polypropylen Syringe Water for Injection 20 mg/ml
Injection   Diamorphine hydrochloride   
Injection   Haloperidol lactate 0,75 mg/ml
18-22°C
20 Day
Light 1886
Level of evidence D
Polypropylen Syringe Water for Injection 0,66 & 33 mg/ml
Injection   Diamorphine hydrochloride   
Injection   Midazolam hydrochloride 0,66 & 5 mg/ml
22°C
14 Day
Protect from light 1288
Level of evidence B
Polypropylen Syringe None 6,25 & 12,5 mg/ml
Injection   Diamorphine hydrochloride   
Injection   Haloperidol lactate 0,31 mg/ml
22°C-24°C
24 Hour
With or without light 779
Level of evidence D
Polypropylen Syringe None 6,25 & 12,5 mg/ml
Injection   Diamorphine hydrochloride   
Injection   Haloperidol lactate 0,31 mg/ml
4-8°C
7 Day
Protect from light 779
Level of evidence D
Polypropylen Syringe Glucose 8% 0,1 mg/ml
Injection   Diamorphine hydrochloride   
Injection   Bupivacaine hydrochloride 4 mg/ml
7°C
26 Day
Not specified 2308
Level of evidence B
Not specified None 0,025 mg/ml
Injection   Diamorphine hydrochloride   
Injection   Ropivacain hydrochloride 2 mg/ml
21°C
28 Day
Not specified 2051
Level of evidence D
Not specified None 0,025 mg/ml
Injection   Diamorphine hydrochloride   
Injection   Ropivacain hydrochloride 2 mg/ml
40°C
6 Day
Not specified 2051
Level of evidence D
Not specified None 0,025 mg/ml
Injection   Diamorphine hydrochloride   
Injection   Ropivacain hydrochloride 2 mg/ml
4°C
70 Day
Not specified 2051
Level of evidence D
  Mentions Légales