Last update :
03/05/2024
References   References 649  
Type : Journal
Web link : http://www.ijpc.com/Abstracts/Abstract.cfm?ABS=414

Research teams : Houston - University of Houston, College of Pharmacy
Authors : Das Gupta V.
Title : Stability of ceftriaxone sodium when mixed with metronidazole injection.
Reference : Int J Pharm Compound ; 1: 280-281. 1997

Level of Evidence : 
Level of evidence B
Physical stability : 
Visual examination 
Chemical stability : 
High Performance Liquid Chromatography - ultraviolet detector (HPLC-UV)
Stability defined as 95% of the initial concentration
Stability defined as 90% of the initial concentration
Other methods : 
PH measurement 
Comments : 

List of drugs
InjectionCeftriaxone disodium Antibiotic
Compatible 10 mg/ml + InjectionMetronidazole 5 mg/ml + None
InjectionMetronidazole Antiparasitic
Compatible 5 mg/ml + InjectionCeftriaxone disodium 10 mg/ml + None
Stability of mixtures
Polyvinyl chloride None 25°C Not specified
Injection Metronidazole 5 mg/ml
Injection Ceftriaxone disodium 10 mg/ml
3 Day

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