Last update :
03/05/2024
Antiemetic   Fosaprepitant dimeglumine  
Injection
Stability in solutions Stability of mixtures Factors which affect stability Compatibility Route of administration References Pdf
   Chemical structure  

Tradename   Tradename     

Trade names are indicative and excipients composition can be different depending on the country and manufacturers

Emend Canada, United States of America
Fosaprepitant
IV-Emend Austria, Great Britain, Japan, Norway, Switzerland
Compatibility   Injection   Compatibility : Fosaprepitant dimeglumine              
This screen indicates the compatibilities or incompatibilities with, in this case, the type of incompatibility (precipitation, color change, modification of an emulsion, etc.). The compatibilities shown here are mostly physical only, with the chemical stability of each molecule rarely being assessed. The evaluation of these mixtures was studied to consider the possibility of Y-site administration to the patient. These data cannot be used for making mixtures in advance in bags or syringes. This type of information is available in the screen "Stability in mixture ».
Compound Solvent References
Unspecified incompatibility Incompatible
Injection Fosaprepitant dimeglumine
Injection Calcium chloride
2295
Unspecified incompatibility Incompatible
Injection Fosaprepitant dimeglumine
Injection Calcium glucoheptonate
2295
Unspecified incompatibility Incompatible
Injection Fosaprepitant dimeglumine
Injection Calcium gluconate
2295
Compatible
Injection Fosaprepitant dimeglumine 1 mg/ml
Injection Dexamethasone sodium phosphate 0,1 mg/ml
Sodium chloride 0,9% 3459
Unspecified incompatibility Incompatible
Injection Fosaprepitant dimeglumine
Injection Folinate calcium
2295
Compatible
Injection Fosaprepitant dimeglumine 1 mg/ml
Injection Granisetron hydrochloride 0,026 mg/ml
Sodium chloride 0,9% 3459
Unspecified incompatibility Incompatible
Injection Fosaprepitant dimeglumine
Injection Levofolinate calcium
2295
Unspecified incompatibility Incompatible
Injection Fosaprepitant dimeglumine
Injection Magnesium sulfate
2295
Compatible
Injection Fosaprepitant dimeglumine 1 mg/ml
Injection Methylprednisolone sodium succinate 0,7 mg/ml
Sodium chloride 0,9% 3459
Compatible
Injection Fosaprepitant dimeglumine 1 mg/ml
Injection Ondansetron hydrochloride 0,07 mg/ml
Sodium chloride 0,9% 3459
Chemical instability Incompatible
Injection Fosaprepitant dimeglumine 1 mg/ml
Injection Palonosetron hydrochloride 2 µg/ml
3459
Chemical instability Incompatible
Injection Fosaprepitant dimeglumine 1 mg/ml
Injection Tropisetron hydrochloride 0,043 mg/ml
Sodium chloride 0,9% 3459
Unspecified incompatibility Incompatible
Injection Fosaprepitant dimeglumine
Ringer’s lactate solution 2295

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