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Anticancer drug   Epirubicin hydrochloride  
Injection
Stability in solutions Stability of mixtures Factors which affect stability Compatibility Route of administration References Pdf
   Chemical structure  

Tradename   Tradename     

Trade names are indicative and excipients composition can be different depending on the country and manufacturers
Anthracine Malaysia
Axirubicine Germany
Bendaepi Germany
Binarin Mexico
Bioepycina Poland
Crisabon Argentina
Cuatroepi Argentina
Ecclepia Romania
Elebicin Mexico
Ellence United States of America
Epi Cell Germany
Epidoxo Argentina, Chile, Venezuela
Epifil Ecuador
Epilem Colombia, Mexico
Epimedac Germany
Epirubicin Australia, Austria, Belgium, Denmark, Great Britain, Hungary, Iceland, New Zealand, Saudi Arabia, Sweden, Switzerland, Turkey
Epirubicina Argentina, Colombia, Ecuador, Mexico, Romania, Spain
Epirubicine Belgium, France, Switzerland
Farmarubicin Turkey
Farmorubicin Austria, Brazil, Denmark, Finland, Greece, Norway, Saudi Arabia, Sweden, Switzerland
Farmorubicin CSV Republic of South Africa
Farmorubicin PFS Croatia, Poland, Slovenia
Farmorubicin RD Brazil, Poland, Russian, Switzerland
Farmorubicin RTU Netherlands
Farmorubicina Brazil, Italy, Portugal, Spain
Farmorubicine Belgium, France
Pharmorubicin Great Britain
Stability in solutions   Injection   Stability in solutions : Epirubicin hydrochloride     
Container Solvent Concentration Temperature Storage Duration of stability References
Glass NaCl 0,9% or Glucose 5% 0.1 mg/ml 2-8°C Protect from light
28 Day
2257
Manufacturer's stability data
Glass NaCl 0,9% or Glucose 5% 0.1 mg/ml 25°C Protect from light
4 Day
2257
Manufacturer's stability data
Glass Sodium chloride 0,9% 0,05 mg/ml 4°C Protect from light
25 Day
525
Level of evidence D
Glass Sodium chloride 0,9% 0.4 mg/ml 2-8°C Protect from light
4 Day
2257
Manufacturer's stability data
Glass Sodium chloride 0,9% 0.4 mg/ml 25°C Protect from light
4 Day
2257
Manufacturer's stability data
Glass Sodium chloride 0,9% 1 & 2 mg/ml 23°C Not specified
150 Day
683
Level of evidence B
Glass Sodium chloride 0,9% 1 & 2 mg/ml 4°C Protect from light
150 Day
683
Level of evidence B
Glass Glucose 5% 0,05 mg/ml 4°C Protect from light
30 Day
525
Level of evidence D
Glass Glucose 5% 1.6 mg/ml 2-8°C Protect from light
4 Day
2257
Manufacturer's stability data
Polyvinyl chloride NaCl 0,9% or Glucose 5% 0,04 mg/ml 4°C Protect from light
7 Day
148
Level of evidence D
Polyvinyl chloride NaCl 0,9% or Glucose 5% 0,1 mg/ml -20°C Protect from light
43 Day
686
Level of evidence C
Polyvinyl chloride NaCl 0,9% or Glucose 5% 0,1 mg/ml 22°C Protect from light
8 Day
1897
Level of evidence D
Polyvinyl chloride NaCl 0,9% or Glucose 5% 0,1 mg/ml 25°C Not specified
20 Day
686
Level of evidence C
Polyvinyl chloride NaCl 0,9% or Glucose 5% 0,1 mg/ml 4°C Protect from light
43 Day
686
Level of evidence C
Polyvinyl chloride NaCl 0,9% or Glucose 5% 0,1 mg/ml 4°C Protect from light
8 Day
1897
Level of evidence D
Polyvinyl chloride NaCl 0,9% or Glucose 5% 0,2 mg/ml 2-8°C Not specified
84 Day
3632
Manufacturer's stability data
Polyvinyl chloride NaCl 0,9% or Glucose 5% 0,2 mg/ml 25 °C Not specified
14 Day
3632
Manufacturer's stability data
Polyvinyl chloride NaCl 0,9% or Glucose 5% 0.1 mg/ml 2-8°C Protect from light
28 Day
2257
Manufacturer's stability data
Polyvinyl chloride NaCl 0,9% or Glucose 5% 0.1 mg/ml 25°C Protect from light
4 Day
2257
Manufacturer's stability data
Polyvinyl chloride NaCl 0,9% or Glucose 5% 1 mg/ml 2-8°C Not specified
84 Day
3632
Manufacturer's stability data
Polyvinyl chloride NaCl 0,9% or Glucose 5% 1 mg/ml 25 °C Not specified
14 Day
3632
Manufacturer's stability data
Polyvinyl chloride Sodium chloride 0,9% 0,02 mg/ml 22°C Light
96 Hour
1897
Level of evidence D
Polyvinyl chloride Sodium chloride 0,9% 0,05 mg/ml 4°C Protect from light
25 Day
525
Level of evidence D
Polyvinyl chloride Sodium chloride 0,9% 1 mg/ml -20°C Protect from light
28 Day
1237
Level of evidence C
Polyvinyl chloride Sodium chloride 0,9% 1.6 mg/ml 2-8°C Protect from light
4 Day
2257
Manufacturer's stability data
Polyvinyl chloride Glucose 5% 0,05 mg/ml 4°C Protect from light
30 Day
525
Level of evidence D
Polyvinyl chloride Glucose 5% 0.4 mg/ml 2-8°C Protect from light
4 Day
2257
Manufacturer's stability data
Polyvinyl chloride Glucose 5% 0.4 mg/ml 25°C Protect from light
4 Day
2257
Manufacturer's stability data
Polyethylene NaCl 0,9% or Glucose 5% 0,1 mg/ml 22°C Protect from light
8 Day
1897
Level of evidence D
Polyethylene NaCl 0,9% or Glucose 5% 0,1 mg/ml 4°C Protect from light
8 Day
1897
Level of evidence D
Polyethylene NaCl 0,9% or Glucose 5% 0.1 mg/ml 2-8°C Protect from light
28 Day
2257
Manufacturer's stability data
Polyethylene NaCl 0,9% or Glucose 5% 0.1 mg/ml 25°C Protect from light
4 Day
2257
Manufacturer's stability data
Polyethylene Sodium chloride 0,9% 0,02 mg/ml 22°C Light
24 Hour
1897
Level of evidence D
Polyethylene Sodium chloride 0,9% 0,05 mg/ml 4°C Protect from light
25 Day
525
Level of evidence D
Polyethylene Glucose 5% 0,02 mg/ml 22°C Light
96 Hour
1897
Level of evidence D
Polyethylene Glucose 5% 0,05 mg/ml 4°C Protect from light
30 Day
525
Level of evidence D
Polypropylene NaCl 0,9% or Glucose 5% 0.1 mg/ml 2-8°C Protect from light
28 Day
2257
Manufacturer's stability data
Polypropylene NaCl 0,9% or Glucose 5% 0.1 mg/ml 25°C Protect from light
4 Day
2257
Manufacturer's stability data
Polypropylen Syringe Water for Injection 2 mg/ml 4°C Protect from light
43 Day
686
Level of evidence C
Polypropylen Syringe Sodium chloride 0,9% 0,5 mg/ml 20°C Not specified
28 Day
1317
Level of evidence D
Polypropylen Syringe Sodium chloride 0,9% 0,5 mg/ml 4°C Protect from light
28 Day
1317
Level of evidence D
Polypropylen Syringe Sodium chloride 0,9% 1 mg/ml 8°C Not specified
84 Day
1823
Level of evidence A
Polypropylen Syringe Sodium chloride 0,9% 1 & 2 mg/ml 23°C Protect from light
150 Day
683
Level of evidence B
Polypropylen Syringe Sodium chloride 0,9% 1 & 2 mg/ml 4°C Protect from light
150 Day
683
Level of evidence B
Polypropylen Syringe Sodium chloride 0,9% 2 mg/ml 25°C With or without light
14 Day
887
Level of evidence C
Polypropylen Syringe Sodium chloride 0,9% 2 mg/ml 4°C Protect from light
180 Day
887
Level of evidence C
Polypropylen Syringe Sodium chloride 0,9% 8.33 mg/ml 4°C Protect from light
72 Hour
3473
Level of evidence A+
Polypropylen Syringe None 2 mg/ml 2-8°C Protect from light
84 Day
3670
Level of evidence A+
  Mentions Légales