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References   References 705  
Type : Journal
Research teams : Mac Gaw Park - American Critical Care
Authors : Lee YC, Malick W, Amann AH, Baaske DM, Shah JJ, Wagenknecht DM, Carter JE.
Title : Bretylium tosylate admixture compatibility. II : Dopamine, lidocaine, procainamide, and nitroglycerin.
Reference : Am J Hosp Pharm ; 38: 183-187. 1981
Level of Evidence : 
Physical stability : 
Chemical stability : 
Other methods : 
Comments : 
List of drugs
InjectionBretylium tosilate Anti-arrhythmic
Compatible 10 mg/ml + InjectionDopamine hydrochloride 0,8 mg/ml + NaCl 0,9% or Glucose 5%
Compatible 10 mg/ml + InjectionLidocaine hydrochloride 1 mg/ml + NaCl 0,9% or Glucose 5%
Compatible 10 mg/ml + InjectionNitroglycerin 0,1 mg/ml + NaCl 0,9% or Glucose 5%
InjectionDopamine hydrochloride Cardiotonic
Compatible 0,8 mg/ml + InjectionBretylium tosilate 10 mg/ml + NaCl 0,9% or Glucose 5%
InjectionLidocaine hydrochloride Local anesthetic
Compatible 1 mg/ml + InjectionBretylium tosilate 10 mg/ml + NaCl 0,9% or Glucose 5%
InjectionNitroglycerin Vasodilator
Compatible 0,1 mg/ml + InjectionBretylium tosilate 10 mg/ml + NaCl 0,9% or Glucose 5%
InjectionProcainamide hydrochloride Anti-arrhythmic
Factors which affect stability Solvent Glucose 5% Induces Degradation
Incompatible + Glucose 5%
Stability of mixtures
Glass NaCl 0,9% or Glucose 5% 25°C Light
Injection Bretylium tosilate 10 mg/ml
Injection Dopamine hydrochloride 0,8 mg/ml
48 Hour
Glass NaCl 0,9% or Glucose 5% 25°C Light
Injection Bretylium tosilate 10 mg/ml
Injection Lidocaine hydrochloride 1 mg/ml
48 Hour
Glass NaCl 0,9% or Glucose 5% 25°C Light
Injection Bretylium tosilate 10 mg/ml
Injection Nitroglycerin 0,1 mg/ml
48 Hour
Glass NaCl 0,9% or Glucose 5% 40°C Protect from light
Injection Bretylium tosilate 10 mg/ml
Injection Dopamine hydrochloride 0,8 mg/ml
48 Hour
Glass NaCl 0,9% or Glucose 5% 40°C Protect from light
Injection Bretylium tosilate 10 mg/ml
Injection Lidocaine hydrochloride 1 mg/ml
48 Hour
Glass NaCl 0,9% or Glucose 5% 40°C Protect from light
Injection Bretylium tosilate 10 mg/ml
Injection Nitroglycerin 0,1 mg/ml
48 Hour
Glass NaCl 0,9% or Glucose 5% 4°C Protect from light
Injection Bretylium tosilate 10 mg/ml
Injection Dopamine hydrochloride 0,8 mg/ml
7 Day
Glass NaCl 0,9% or Glucose 5% 4°C Protect from light
Injection Bretylium tosilate 10 mg/ml
Injection Lidocaine hydrochloride 1 mg/ml
7 Day
Glass NaCl 0,9% or Glucose 5% 4°C Protect from light
Injection Bretylium tosilate 10 mg/ml
Injection Nitroglycerin 0,1 mg/ml
7 Day
Polyvinyl chloride NaCl 0,9% or Glucose 5% 25°C Light
Injection Bretylium tosilate 10 mg/ml
Injection Lidocaine hydrochloride 1 mg/ml
48 Hour
Polyvinyl chloride NaCl 0,9% or Glucose 5% 40°C Protect from light
Injection Bretylium tosilate 10 mg/ml
Injection Lidocaine hydrochloride 1 mg/ml
48 Hour
Polyvinyl chloride NaCl 0,9% or Glucose 5% 4°C Protect from light
Injection Bretylium tosilate 10 mg/ml
Injection Lidocaine hydrochloride 1 mg/ml
7 Day
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