Last update :
28/04/2024
References   References 636  
Type : Journal

Research teams : Houston - University of Houston, College of Pharmacy
Authors : Das Gupta V, Stewart KR.
Title : Stability of cefuroxime sodium in some aqueous buffered solutions and intravenous admixtures.
Reference : J Clin Hosp Pharm ; 11: 47-54. 1986

Level of Evidence : 
Level of evidence B
Physical stability : 
Visual examination 
Chemical stability : 
High Performance Liquid Chromatography - ultraviolet detector (HPLC-UV)
Stability defined as 90% of the initial concentration
Other methods : 
PH measurement 
Comments : 

List of drugs
InjectionCefuroxime sodium Antibiotic
Factors which affect stability Micro-waves Induces Degradation
Stability in solutions Glass NaCl 0,9% or Glucose 5% 5 & 10 mg/ml -10°C Protect from light
30 Day
Stability in solutions Glass NaCl 0,9% or Glucose 5% 5 & 10 mg/ml 25°C Not specified
24 Hour
Stability in solutions Glass NaCl 0,9% or Glucose 5% 5 & 10 mg/ml 5°C Protect from light
30 Day
Stability in solutions Polyvinyl chloride NaCl 0,9% or Glucose 5% 5 & 10 mg/ml -10°C Protect from light
30 Day
Stability in solutions Polyvinyl chloride NaCl 0,9% or Glucose 5% 5 & 10 mg/ml 25°C Not specified
24 Hour
Stability in solutions Polyvinyl chloride NaCl 0,9% or Glucose 5% 5 & 10 mg/ml 5°C Protect from light
30 Day

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