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References   References 2867  
Type : Journal
Web link : http://www.ijpc.com/Abstracts/Abstract.cfm?ABS=482
Research teams : Marseille - Marseille North Hospital, Department of Pharmacy
Authors : Peyron F, Elias R, Ibrahim E, Amirat-Combralier V, Bu?s-Charbit M, Balansard G.
Title : Stability of Amphotericin B in 5% Dextrose Ophthalmic Solution.
Reference : Int J Pharm Compound ; 3, 4: 316-320. 1999
Level of Evidence : 
Physical stability : 
Visual examination 
Chemical stability : 
High Performance Liquid Chromatography - ultraviolet detector (HPLC-UV)
Other methods : 
PH measurement Measurement of osmolality 
Comments : 
List of drugs
Eye-dropsAmphotericin B Antifungal
Factors which affect stability Temperature 25°C Induces Reduced stability
Stability in solutions Plastic bottle Medicine bottle for injection 15 mg
Fungizone®
Dextrose 5% >> 3 ml
2-6°C Protect from light
120 Day
Stability in solutions Plastic bottle Medicine bottle for injection 15 mg
Fungizone®
Dextrose 5% >> 3 ml
20-25°C Protect from light
16 Day
Stability in solutions Plastic bottle Medicine bottle for injection 15 mg
Fungizone®
Dextrose 5% >> 3 ml
20-25°C Light
13 Day
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