Last update :
28/04/2024
References   References 2487  
Type : Journal
Web link : http://www.ajhp.org/cgi/content/abstract/48/3/507

Research teams : Birmingham - Samford University, School of Pharmacy
Authors : McBride HA, Martinez DR, Trang JM, Lander RD, Helms HA.
Title : Stability of gentamicin sulfate and tobramycin sulfate in extemporaneously prepared ophthalmic solutions at 8 degrees C
Reference : Am J Hosp Pharm ; 48: 507-509. 1991

Level of Evidence : 
Physical stability : 
Chemical stability : 
High Performance Liquid Chromatography - ultraviolet detector (HPLC-UV)
Stability defined as 95% of the initial concentration
Other methods : 
Comments : 
No visual inspection

List of drugs
Eye-dropsGentamicin sulfate Antibiotic
Stability in solutions Plastic bottle Medicine bottle for injection 5 ml
gentamycine sulfate 40 mg/ml ®=? (Lyphomed)
Genoptic® eye-drops 3 mg/ml 2 ml
4-8°C Protect from light
90 Day
Eye-dropsTobramycin sulfate Antibiotic
Stability in solutions Plastic bottle Medicine bottle for injection 5 ml
Nebcin® 40 mg/ml
Tobrex® 3 mg/ml eye-drops 2 ml
4-8°C Protect from light
90 Day

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