Last update :
18/04/2024
References   References 240  
Type : Journal
Web link : http://www.ajhp.org/cgi/content/abstract/52/17/1904

Research teams : San Francisco - Genentech, Inc
Authors : Lam XM, Ward CA, de C du M?e CPR.
Title : Stability and activity of alteplase with injectable drugs commonly used in cardiac therapy.
Reference : Am J Health-Syst Pharm ; 52: 1904-1909. 1995

Level of Evidence : 
Physical stability : 
Chemical stability : 
Other methods : 
Comments : 

List of drugs
InjectionAlteplase Thrombolytic
Incompatible 0.5 mg/ml + InjectionDobutamine hydrochloride 5 mg/ml + Water for Injection
Incompatible 0.5 mg/ml + InjectionDopamine hydrochloride 0.8 mg/ml + Water for Injection
Incompatible 0.5 mg/ml + InjectionHeparin sodium 40 UI/ml + Water for Injection
Compatible 0.5 mg/ml + InjectionLidocaine hydrochloride 4 mg/ml + Water for Injection
Compatible 0.5 mg/ml + InjectionMetoprolol tartrate 0.5 mg/ml + Water for Injection
Incompatible 0.5 mg/ml + InjectionMorphine sulfate 1 mg/ml + Water for Injection
Compatible 0.5 mg/ml + InjectionNitroglycerin 0.4 mg/ml + Water for Injection
Compatible 0.5 mg/ml + InjectionPropranolol hydrochloride 0.5 mg/ml + Water for Injection
InjectionDobutamine hydrochloride Cardiotonic
Incompatible 5 mg/ml + InjectionAlteplase 0.5 mg/ml + Water for Injection
InjectionDopamine hydrochloride Cardiotonic
Incompatible 0.8 mg/ml + InjectionAlteplase 0.5 mg/ml + Water for Injection
InjectionHeparin sodium Anticoagulant
Incompatible 40 UI/ml + InjectionAlteplase 0.5 mg/ml + Water for Injection
InjectionLidocaine hydrochloride Local anesthetic
Compatible 4 mg/ml + InjectionAlteplase 0.5 mg/ml + Water for Injection
InjectionMetoprolol tartrate Anti-arrhythmic
Compatible 0.5 mg/ml + InjectionAlteplase 0.5 mg/ml + Water for Injection
InjectionMorphine sulfate Analgesic
Incompatible 1 mg/ml + InjectionAlteplase 0.5 mg/ml + Water for Injection
InjectionNitroglycerin Vasodilator
Compatible 0.4 mg/ml + InjectionAlteplase 0.5 mg/ml + Water for Injection
InjectionPropranolol hydrochloride Beta-blocker
Compatible 0.5 mg/ml + InjectionAlteplase 0.5 mg/ml + Water for Injection

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