Bibliographie - 2340 - Stabilis 4.0

Last update :
28/04/2024

References 2340

Type :

Journal

Web link :

Research teams :

Toronto - Sunnybrook Health Sciences Center

Authors :

Walker S.E, Law S, Puodziunas A.

Title :

Simulation of Y-Site Compatibility of Irinotecan and Leucovorin at Room Temperature in 5% Dextrose in Water in 3 Different Containers

Reference :

Can J Hosp Pharm ; 58, 4: 212-222. 2005

Level of Evidence :

Physical stability :

Chemical stability :

Other methods :

Comments :

Degradation products identified

List of drugs

	0,23 >> 0,95 mg/ml	+ Irinotecan	0,31 >> 0,65 mg/ml	+
	3,55 >> 3,67 mg/ml	+ Irinotecan	0,34 >> 0,35 mg/ml	+

Irinotecan

	0,31 >> 0,65 mg/ml	+ Folinate calcium	0,23 >> 0,95 mg/ml	+
	0,34 >> 0,35 mg/ml	+ Folinate calcium	3,55 >> 3,67 mg/ml	+

23°C

Folinate calcium	0,23 >> 0.95 mg/ml
Irinotecan	0,31 >> 0,65 mg/ml

0.5

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