Last update :
03/05/2024
References   References 22  
Type : Journal

Research teams : Exeter - University of Exeter
Authors : Sewell GJ, Palmer AJ.
Title : The chemical and physical stability of three intravenous infusions subjected to frozen storage and microwave thawing.
Reference : Int J Pharm ; 72: 57-63. 1991

Level of Evidence : 
Level of evidence A+
Physical stability : 
Particle counting 
Chemical stability : 
High Performance Liquid Chromatography - Diode Array detector (HPLD-DAD)
Stability defined as 95% of the initial concentration
Other methods : 
PH measurement Water loss by evaporation 
Comments : 

List of drugs
InjectionErythromycin lactobionate Antibiotic
Stability in solutions Polyvinyl chloride Sodium chloride 0,9% 4,54 mg/ml -20°C Protect from light
365 Day
InjectionFusidate sodium Antibiotic
Stability in solutions Polyvinyl chloride Sodium chloride 0,9% 0,9 mg/ml -20°C Protect from light
365 Day
InjectionMethylprednisolone sodium succinate Anti-inflammatory
Stability in solutions Polyvinyl chloride Sodium chloride 0,9% 4,6 mg/ml -20°C Protect from light
365 Day

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