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References   References 1904  
Type : Journal
Web link : http://www.ajhp.org/cgi/content/abstract/60/9/916
Research teams : Research Triangle Park - United Therapeutics corporation
Authors : Phares KR, Weiser WE, Miller SP, Myers MA, Wade M.
Title : Stability and preservative effectiveness of treprostinil sodium after dilution in common intravenous diluents.
Reference : Am J Health-Syst Pharm ; 60: 916-922. 2003
Level of Evidence : 
Level of evidence A
Physical stability : 
Visual examination 
Chemical stability : 
High Performance Liquid Chromatography - ultraviolet detector (HPLC-UV)
Stability defined as 95% of the initial concentration
Other methods : 
PH measurement 
Comments : 
List of drugs
InjectionTreprostinil Vasodilator
Stability in solutions Polyvinyl chloride Water for Injection 0,004 & 0,13 mg/ml 40°C Not specified
48 Hour
Stability in solutions Polyvinyl chloride NaCl 0,9% or Glucose 5% 0,13 mg/ml 40°C Not specified
48 Hour
Stability in solutions Polyvinyl chloride Sodium chloride 0,9% 0,004 mg/ml 40°C Not specified
48 Hour
Stability in solutions Polyvinyl chloride Glucose 5% 0,02 mg/ml 40°C Not specified
48 Hour
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