Last update :
08/05/2024
References   References 1419  
Type : Journal
Web link : http://www.ijpc.com/Abstracts/Abstract.cfm?ABS=943

Research teams : Birmingham - Samford University, School of Pharmacy
Authors : Riggs RM, English BA, Webster AA, McGuire JM, Riordan JM.
Title : Fosphenytoin Y-site stability studies with lorazepam and midazolam hydrochloride.
Reference : Int J Pharm Compound ; 3: 235-238. 1999

Level of Evidence : 
Physical stability : 
Chemical stability : 
Other methods : 
Comments : 

List of drugs
InjectionFosphenytoin sodium Antiepileptic
Compatible 5 mg/ml + InjectionLorazepam 1 mg/ml + Sodium chloride 0,9%
Incompatible 5 mg/ml + InjectionMidazolam hydrochloride 2 mg/ml + Sodium chloride 0,9%
InjectionLorazepam Anxiolytic
Compatible 1 mg/ml + InjectionFosphenytoin sodium 5 mg/ml + Sodium chloride 0,9%
InjectionMidazolam hydrochloride Anxiolytic
Incompatible 2 mg/ml + InjectionFosphenytoin sodium 5 mg/ml + Sodium chloride 0,9%
Stability of mixtures
Glass Sodium chloride 0,9% 25°C Not specified
Injection Fosphenytoin sodium 5 mg/ml
Injection Lorazepam 1 mg/ml
8 Hour

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