Last update :
03/05/2024
References   References 1239  
Type : Journal

Research teams : Utrecht - Faculty of pharmacy, State university of Utrecht
Authors : Stolk LML, Fruijtier A, Umans .
Title : Stability after freezing and thawing of solutions of mitomycin C in plastic minibags for intravesical use.
Reference : Pharm Weekbl [Sci] ; 8: 286-288. 1986

Level of Evidence : 
Level of evidence D
Physical stability : 
Visual examination 
Chemical stability : 
Stability defined as 95% of the initial concentration
High Performance Liquid Chromatography - ultraviolet detector (HPLC-UV)
Other methods : 
PH measurement 
Comments : 
Stability indicating capability inadequately assessed
Repeatability / reproducibility / standard range: results not provided or results outside specified values
Imperfect separation of the internal standard from the product under study or its degradation products, or understudied
No comments for the degradation products

List of drugs
InjectionMitomycin Anticancer drug
Factors which affect stability Temperature -20°C Induces Precipitation
Stability in solutions Polyvinyl chloride Sodium chloride 0,9% 0.6 mg/ml -30°C Protect from light
30 Day

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