Last update :
28/04/2024
References   References 1046  
Type : Journal

Research teams : Athens - University of Georgia, College of Pharmacy
Authors : Stewart JT, Maddox FC, Warren FW.
Title : Stability of cefepime hydrochloride in polypropylene syringes.
Reference : Am J Health-Syst Pharm ; 56: 1134. 1999

Level of Evidence : 
Level of evidence B
Physical stability : 
Visual examination 
Chemical stability : 
Stability defined as 90% of the initial concentration
High Performance Liquid Chromatography - Diode Array detector (HPLD-DAD)
Other methods : 
PH measurement 
Comments : 

List of drugs
InjectionCefepime dihydrochloride Antibiotic
Stability in solutions Polypropylen Syringe Water for Injection 100 & 200 mg/ml 22-24°C Not specified
2 Day
Stability in solutions Polypropylen Syringe Water for Injection 100 & 200 mg/ml 4°C Protect from light
14 Day
Stability in solutions Polypropylen Syringe NaCl 0,9% or Glucose 5% 200 mg/ml 22-24°C Not specified
2 Day
Stability in solutions Polypropylen Syringe NaCl 0,9% or Glucose 5% 200 mg/ml 4°C Protect from light
14 Day
Stability in solutions Polypropylen Syringe Sodium chloride 0,9% 100 mg/ml 22°C-24°C Not specified
2 Day
Stability in solutions Polypropylen Syringe Glucose 5% 100 mg/ml 22°C-24°C Not specified
1 Day

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