Last update :
18/04/2024
References   References 100  
Type : Journal

Research teams : Fremantle - Fremantle Hospital, Department of Pharmacy
Authors : Plumridge RJ, Rieck AM, Annus TP, Langton SR.
Title : Stability of ceftriaxone sodium in polypropylene syringes at -20, 4, and 20°C.
Reference : Am J Health-Syst Pharm ; 43: 2320-2323. 1996

Level of Evidence : 
Level of evidence D
Physical stability : 
Visual examination 
Chemical stability : 
High Performance Liquid Chromatography - ultraviolet detector (HPLC-UV)
Other methods : 
PH measurement 
Comments : 
Imperfect separation of the internal standard from the product under study or its degradation products, or understudied
No comments for the degradation products

List of drugs
InjectionCeftriaxone disodium Antibiotic
Factors which affect stability Temperature Increase Induces Degradation
Stability in solutions Polypropylen Syringe Water for Injection 100 mg/ml -20°C Protect from light
180 Day
Stability in solutions Polypropylen Syringe Water for Injection 100 mg/ml 20°C Protect from light
5 Day
Stability in solutions Polypropylen Syringe Water for Injection 100 mg/ml 4°C Protect from light
40 Day

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