Last update :
21/01/2026
References   References 693  
Type : Journal

Research teams : Houston - University of Houston, College of Pharmacy
Authors : Das Gupta V, Parasrampuria J, Bethea C.
Title : Chemical stabilities of famotidine and ranitidine hydrochloride in intravenous admixtures.
Reference : J Clin Pharm Ther ; 13: 329-334. 1988

Level of Evidence : 
Level of evidence D
Physical stability : 
Visual examination 
Chemical stability : 
High Performance Liquid Chromatography - ultraviolet detector (HPLC-UV)
Other methods : 
PH measurement 
Comments : 
Imperfect separation of the internal standard from the product under study or its degradation products, or understudied

List of drugs
injectionFamotidine Antihistamine (H2)
Stability in solutions Polyvinyl chloride Sodium chloride 0,9% 0,2 mg/ml 25°C Not specified
15 Day
Stability in solutions Polyvinyl chloride Sodium chloride 0,9% 0,2 mg/ml 4°C Protect from light
63 Day
Stability in solutions Polyvinyl chloride Glucose 5% 0,2 mg/ml 25°C Not specified
15 Day
Stability in solutions Polyvinyl chloride Glucose 5% 0,2 mg/ml 4°C Protect from light
63 Day
injectionRanitidine hydrochloride Antihistamine (H2)
Stability in solutions Polyvinyl chloride Sodium chloride 0,9% 1 mg/ml 25°C Not specified
15 Day
Stability in solutions Polyvinyl chloride Sodium chloride 0,9% 1 mg/ml 5°C Protect from light
63 Day
Stability in solutions Polyvinyl chloride Glucose 5% 1 mg/ml 25°C Not specified
15 Day
Stability in solutions Polyvinyl chloride Glucose 5% 1 mg/ml 5°C Protect from light
63 Day

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