| Type : |
Journal |
| Internet-link : |
https://ijpc.com/Abstracts/Abstract.cfm?ABS=857 |
|
| forskerhold : |
Tolède - College of Pharmacy and Pharmaceutical Sciences, The University of Toledo |
| Forfattere : |
Alexander KS, Sundar S, White DB, Dollimore D. |
| Titel : |
The Formulation Development and Stability of Spironolactone Suspension |
| Nummer : |
Int J Pharm Compound ; 1, 3: 195-199. 1997 |
|
| bevisniveau : |
|
| fysisk stabilitet : |
|
| kemisk stabilitet : |
|
| andre metoder : |
|
| Kommentarer : |
|
Lister
 Spironolactone
|
 |
 |
pH |
pH 4.5 |
 |
 |
 |
 |
 |
600 mg
®= ? |
| Carboxymethylcellulose |
900 mg |
| Veegum® |
900 mg |
| Methylparaben |
120 mg |
| Propylparaben |
24 mg |
| Propylenglycol |
1.2 ml |
| Sorbitol |
70% 48 ml |
| Natriumacetat |
350 mg |
| Eddikesyre |
36% 0.67 ml |
| Natriumbisulfit |
120 mg |
| Natriumedetat |
120 mg |
| Natriumsaccharin |
24 mg |
| Ananasaroma |
|
| Destilleret vand |
>> 120 ml |
|
30°C |
 |
| 90 |
 |
|
|
|
|
|
600 mg
®= ? |
| Carboxymethylcellulose |
900 mg |
| Veegum® |
900 mg |
| Methylparaben |
120 mg |
| Propylparaben |
24 mg |
| Propylenglycol |
1.2 ml |
| Sorbitol |
70% 48 ml |
| Natriumacetat |
350 mg |
| Eddikesyre |
36% 0.67 ml |
| Natriumbisulfit |
120 mg |
| Natriumedetat |
120 mg |
| Natriumsaccharin |
24 mg |
| Ananasaroma |
|
| Destilleret vand |
>> 120 ml |
|
5°C |
|
| 90 |
|
|
|
|
|
