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Anticancer drug   Aflibercept  
injection
Stability in solutions Stability of mixtures Factors which affect stability Compatibility Route of administration References pdf

Tradename   Tradename     

Trade names are indicative and excipients composition can be different depending on the country and manufacturers
Zaltrap Belgium, Brazil, Canada, Chile, Denmark, Ecuador, Finland, France, Germany, Great Britain, Hungary, Iceland, Ireland, Italy, Luxembourg, Mexico, Norway, Peru, Romania, Slovenia, Spain, Sweden, Switzerland, Turkey, United States of America
Zaltrapziv Mexico
Stability in solutions   injection   Stability in solutions : Aflibercept     
Container Solvent Concentration Temperature Storage Duration of stability References
Polyvinyl chloride Sodium chloride 0,9% 0,6 >> 8 mg/ml 2-8°C Not specified
24 Hour
3508
Manufacturer's stability data
Polyvinyl chloride Sodium chloride 0,9% 0,6 >> 8 mg/ml 25°C Light
8 Hour
3508
Manufacturer's stability data
Polyvinyl chloride Glucose 5% 0,6 >> 8 mg/ml 2-8°C Not specified
24 Hour
3508
Manufacturer's stability data
Polyvinyl chloride Glucose 5% 0,6 >> 8 mg/ml 25°C Light
8 Hour
3508
Manufacturer's stability data
Polyolefine Sodium chloride 0,9% 0,6 mg/ml 2-8°C Protect from light
14 Day
4728
Level of evidence A+
Polyolefine Sodium chloride 0,9% 0,6 >> 8 mg/ml 2-8°C Not specified
24 Hour
3508
Manufacturer's stability data
Polyolefine Sodium chloride 0,9% 0,6 >> 8 mg/ml 25°C Light
8 Hour
3508
Manufacturer's stability data
Polyolefine Sodium chloride 0,9% 4 mg/ml 2-8°C Protect from light
14 Day
4728
Level of evidence A+
Polyolefine Glucose 5% 0,6 >> 8 mg/ml 2-8°C Not specified
24 Hour
3508
Manufacturer's stability data
Polyolefine Glucose 5% 0,6 >> 8 mg/ml 25°C Light
8 Hour
3508
Manufacturer's stability data
Polypropylen Syringe None 40 mg/ml 4°C Protect from light
30 Day
4798
  Mentions Légales