Last update :
03/05/2024
Anticancer drug   Mitomycin  
Injection
Stability in solutions Stability of mixtures Factors which affect stability Compatibility Route of administration References Pdf
   Chemical structure  

Tradename   Tradename     

Trade names are indicative and excipients composition can be different depending on the country and manufacturers

Ametycine France
Crisofimina Argentina
Fatrix Chile
Maximitom Argentina
Maximiton Ecuador
Minazol Colombia
Mitameta Italy
Mitem Germany, Switzerland
Mitocin Brazil
Mitokebir Argentina, Ecuador
Mitolem Colombia, Venezuela
Mitomicina Argentina, Chile, Ecuador, Italy, Mexico, Peru, Portugal, Romania, Spain
Mitomycin Austria, Belgium, Denmark, Finland, Germany, Great Britain, Greece, Hungary, Iran, Ireland, Italy, Malaysia, New Zealand, Norway, Poland, Slovenia, Sweden, Turkey, United States of America
Mitomycine Luxembourg, Netherlands
Mitotie Argentina, Chile, Ecuador, Peru
Mitozytrex United States of America
Mixandex Colombia, Mexico
Mutamycin United States of America
Riptam Colombia
Ronzine Argentina, Peru
Urocin Germany

Factors which affect stability   Injection   Factors which affect stability : Mitomycin        
References
Storage 4°C[ > 0,6 mg / ml] Induces Precipitation 1827
Solvent Glucose 5% Induces Degradation 1178
Temperature Increase Induces Degradation 485
Temperature -20°C Induces Precipitation 1239
Temperature -20°C[ 1 mg/ ml] Induces Degradation 4526
PH Reduction Induces Degradation 485
PH Increase Induces Enhanced stability 407
PH PH < 5 Induces Degradation 835
PH PH >10 Induces Degradation 3575
4471
PH PH > 9 Induces Degradation 835
PH PH < 5.6 Induces Degradation 3575
4471

  Mentions Légales