Last update :
28/04/2024
Vasodilator   Nitroprusside sodium  
Injection
Stability in solutions Stability of mixtures Factors which affect stability Compatibility Route of administration References Pdf
   Chemical structure  

Tradename   Tradename     

Trade names are indicative and excipients composition can be different depending on the country and manufacturers

Nipride Canada, Netherlands
Nipruss Egypt, Germany
Nitropress Iran, New Zealand, United States of America
Nitroprussiate FID France
Stability of mixtures   Injection   Stability of mixtures : Nitroprusside sodium     
Container Solvent Concentration Compound Temperature Storage Duration of stability References
Glass Sodium chloride 0,9% 0,2 mg/ml
Injection   Nitroprusside sodium   
Injection   Dobutamine hydrochloride 2 mg/ml
Injection   Nitroglycerin 0,2 mg/ml
?
24 Hour
Not specified 1109
Glass Glucose 5% 1,2 mg/ml
Injection   Nitroprusside sodium   
Injection   Dobutamine hydrochloride 5 mg/ml
22°C
24 Hour
Protect from light 3381
Glass Glucose 5% 0,4 mg/ml
Injection   Nitroprusside sodium   
Injection   Milrinone lactate 0,2 mg/ml
22°C-23°C
4 Hour
Protect from light 813
Level of evidence A
Polyvinyl chloride NaCl 0,9% or Glucose 5% 0,05 & 0,4 mg/ml
Injection   Nitroprusside sodium   
Injection   Ranitidine hydrochloride 0,05 & 2 mg/ml
?
48 Hour
Not specified 210
Level of evidence B
Polyethylene Glucose 5% 1,2 mg/ml
Injection   Nitroprusside sodium   
Injection   Dobutamine hydrochloride 5 mg/ml
22°C
24 Hour
Protect from light 3381
Not specified Sodium chloride 0,9% 0,18 mg/ml
Injection   Nitroprusside sodium   
Injection   Sodium thiosulfate 1,8 mg/ml
25°C
48 Hour
Protect from light 4020
Level of evidence C
Not specified Glucose 5% 0,2 mg/ml
Injection   Nitroprusside sodium   
Injection   Esmolol hydrochloride 10 mg/ml
15-30°C
24 Hour
Protect from light 363
Level of evidence A+
Not specified Glucose 5% 0,18 mg/ml
Injection   Nitroprusside sodium   
Injection   Sodium thiosulfate 1,8 mg/ml
25°C
48 Hour
Protect from light 4020
Level of evidence C

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