Last update :
18/04/2024
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General anesthetic   Propofol  
Injection
Stability in solutions Stability of mixtures Factors which affect stability Compatibility Route of administration References Pdf
   Chemical structure  

Tradename   Tradename     

Trade names are indicative and excipients composition can be different depending on the country and manufacturers
Abbofol Poland
Anesia Germany
Diprivan Argentina, Australia, Austria, Canada, Chile, Colombia, Denmark, Egypt, Finland, France, Great Britain, Hungary, Iran, Ireland, Italy, Luxembourg, Mexico, Morocco, Netherlands, New Zealand, Peru, Poland, Portugal, Saudi Arabia, Spain, Sweden, Tunisia, Turkey, United States of America, Venezuela
Diprofol Ireland
Disoprivan Germany, Switzerland
Fresofol Argentina, Colombia, India, Malaysia, Mexico, New Zealand
Gobbifol Argentina
Indufol Colombia
Plofed Poland
Pofol Turkey
Propolipid Germany, Norway, Sweden
Propovan Argentina
Recofol Egypt, Finland, Iran, Saudi Arabia, Spain, United Arab Emirates
Troypofol Colombia, United Arab Emirates
Stability of mixtures   Injection   Stability of mixtures : Propofol     
Container Solvent Concentration Compound Temperature Storage Duration of stability References
Glass Glucose 5% 5,3 mg/ml
Injection   Propofol   
Injection   Milrinone lactate 0,2 mg/ml
22°C-23°C
4 Hour
Light 813
Level of evidence A
Glass None 5 mg/ml
Injection   Propofol   
Injection   Thiopental sodium 12,5 mg/ml
25°C
6 Hour
Not specified 126
Level of evidence A+
Polypropylene Sodium chloride 0,9% 1 & 5 mg/ml
Injection   Propofol   
Injection   Ondansetron hydrochloride 1 mg/ml
23°C
24 Hour
Light 815
Level of evidence C+
Polypropylene Sodium chloride 0,9% 6,7 mg/ml
Injection   Propofol   
Injection   Sufentanil citrate 0,0033 mg/ml
Injection   Midazolam hydrochloride 1,2 mg/ml
25°C
24 Hour
Light 4011
Level of evidence C+
Polypropylene Sodium chloride 0,9% 6,7 mg/ml
Injection   Propofol   
Injection   Sufentanil citrate 0,0033 mg/ml
Injection   Piritramide 0,33 mg/ml
25°C
24 Hour
Light 4011
Level of evidence C+
Polypropylene Sodium chloride 0,9% 5 mg/ml
Injection   Propofol   
Injection   Sufentanil citrate 0,0075 mg/ml
Injection   Midazolam hydrochloride 0,9 mg/ml
Injection   Lormetazepam 0,03 mg/ml
25°C
24 Hour
Light 4011
Level of evidence C+
Polypropylene Sodium chloride 0,9% 6,7 mg/ml
Injection   Propofol   
Injection   Dexmedetomidine 6,6 µg/ml
Injection   Sufentanil citrate 0,01 mg/ml
25°C
24 Hour
Light 4011
Level of evidence C+
Polypropylene Sodium chloride 0,9% 6,7 mg/ml
Injection   Propofol   
Injection   Sufentanil citrate 0,01 mg/ml
Injection   Clonidine hydrochloride 0,005 mg/ml
25°C
24 Hour
Light 4011
Level of evidence C+
Polypropylene Sodium chloride 0,9% 6,7 mg/ml
Injection   Propofol   
Injection   Midazolam hydrochloride 1,2 mg/ml
Injection   Remifentanil hydrochloride 1,7 µg/ml
25°C
24 Hour
Light 4011
Level of evidence C+
Polypropylene Sodium chloride 0,9% 10 mg/ml
Injection   Propofol   
Injection   Clonidine hydrochloride 0,0075 mg/ml
25°C
24 Hour
Light 4011
Level of evidence C+
Polypropylene Sodium chloride 0,9% 1,8 mg/ml
Injection   Propofol   
Injection   Clonidine hydrochloride 0,0136 mg/ml
25°C
24 Hour
Light 4011
Level of evidence C+
Polypropylene Sodium chloride 0,9% 18 mg/ml
Injection   Propofol   
Injection   Clonidine hydrochloride 0,00136 mg/ml
25°C
24 Hour
Light 4011
Level of evidence C+
Polypropylene Sodium chloride 0,9% 18 mg/ml
Injection   Propofol   
Injection   Dexmedetomidine 1,81 µg/ml
25°C
24 Hour
Light 4011
Level of evidence C+
Polypropylene Sodium chloride 0,9% 1,8 mg/ml
Injection   Propofol   
Injection   Dexmedetomidine 18,1 µg/ml
25°C
24 Hour
Light 4011
Level of evidence C+
Polypropylene Sodium chloride 0,9% 10 mg/ml
Injection   Propofol   
Injection   Dexmedetomidine 10 µg/ml
25°C
24 Hour
Light 4011
Level of evidence C+
Polypropylene Sodium chloride 0,9% 10 mg/ml
Injection   Propofol    Conflicting data
Injection   Ketamine hydrochloride 12,5 mg/ml Conflicting data
25°C
24 Hour
Light 4011
Level of evidence C+
Polypropylene Sodium chloride 0,9% 1,8 mg/ml
Injection   Propofol    Conflicting data
Injection   Ketamine hydrochloride 22,7 mg/ml Conflicting data
25°C
24 Hour
Light 4011
Level of evidence C+
Polypropylene Sodium chloride 0,9% 18 mg/ml
Injection   Propofol    Conflicting data
Injection   Ketamine hydrochloride 2,27 mg/ml Conflicting data
25°C
24 Hour
Light 4011
Level of evidence C+
Polypropylene Sodium chloride 0,9% 18 mg/ml
Injection   Propofol   
Injection   Lormetazepam 0,009 mg/ml
25°C
24 Hour
Light 4011
Level of evidence C+
Polypropylene Sodium chloride 0,9% 1,8 mg/ml
Injection   Propofol   
Injection   Lormetazepam 0,09 mg/ml
25°C
24 Hour
Light 4011
Level of evidence C+
Polypropylene Sodium chloride 0,9% 10 mg/ml
Injection   Propofol   
Injection   Lormetazepam 0,06 mg/ml
25°C
24 Hour
Light 4011
Level of evidence C+
Polypropylene Sodium chloride 0,9% 10 mg/ml
Injection   Propofol   
Injection   Sufentanil citrate 0,015 mg/ml
25°C
24 Hour
Light 4011
Level of evidence C+
Polypropylene Sodium chloride 0,9% 1,8 mg/ml
Injection   Propofol   
Injection   Sufentanil citrate 0,027 mg/ml
25°C
24 Hour
Light 4011
Level of evidence C+
Polypropylene Sodium chloride 0,9% 18 mg/ml
Injection   Propofol   
Injection   Sufentanil citrate 0,0027 mg/ml
25°C
24 Hour
Light 4011
Level of evidence C+
Polypropylene None 5 mg/ml
Injection   Propofol   
Injection   Thiopental sodium 12,5 mg/ml
23°C
5 Day
Light 125
Level of evidence B
Polypropylene None 5 mg/ml
Injection   Propofol   
Injection   Thiopental sodium 12,5 mg/ml
23°C
7 Day
Not specified 919
Polypropylene None 5 mg/ml
Injection   Propofol   
Injection   Palonosetron hydrochloride 25 µg/ml
25°C
4 Hour
Light 2312
Level of evidence A
Polypropylene None 5 mg/ml
Injection   Propofol   
Injection   Thiopental sodium 12,5 mg/ml
4°C
7 Day
Protect from light 919
Polypropylene None 5 mg/ml
Injection   Propofol   
Injection   Thiopental sodium 12,5 mg/ml
4°C
13 Day
Protect from light 125
Level of evidence B
Polypropylen Syringe None 0,0095 mg/ml
Injection   Propofol   
Injection   Vecuronium bromide 0,127 mg/ml
Injection   Fentanyl citrate 0,0024 µg/ml
22°C
1 Hour
Protect from light 1863
Polypropylen Syringe None 4,9 mg/ml
Injection   Propofol    Conflicting data
Injection   Ketamine hydrochloride 5,2 mg/ml Conflicting data
23°C
3 Hour
Light 2329
Polypropylen Syringe None 6,8 mg/ml
Injection   Propofol    Conflicting data
Injection   Ketamine hydrochloride 3,3 mg/ml Conflicting data
23°C
3 Hour
Light 2329
  Mentions Légales