Last update :
18/04/2024
References   References 840  
Type : Journal

Research teams : Toronto - University of Toronto, Faculty of Pharmacy
Authors : Biondi L, Nairn JG.
Title : Stability of 5-fluorouracil and flucytosine in parenteral solutions.
Reference : Can J Hosp Pharm ; 39: 60-66. 1986

Level of Evidence : 
Level of evidence D
Physical stability : 
Chemical stability : 
Stability defined as 90% of the initial concentration
High Performance Liquid Chromatography - ultraviolet detector (HPLC-UV)
Other methods : 
PH measurement 
Comments : 
Repeatability / reproducibility / standard range: results not provided or results outside specified values
Results with high coefficient of variation or not provided, or lack of duplicate analysis of each point
No comments for the degradation products

List of drugs
InjectionFluorouracil Anticancer drug
Stability in solutions Glass NaCl 0,9% or Glucose 5% 1,5 mg/ml 25°C With or without light
56 Day
Stability in solutions Polyvinyl chloride NaCl 0,9% or Glucose 5% 1,5 mg/ml 25°C With or without light
56 Day

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