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References   References 828  
Type : Journal
Research teams : Oullins - Laboratoire Lederlé, Recherche et Développement
Authors : Lecompte D, Bousselet M, Magnam J.
Title : Stability of mitoxantrone (Novantrone*) after dilution in PVC infusions.
Reference : J Pharm Clin ; 9: 159-165. 1990
Level of Evidence : 
Level of evidence B
Physical stability : 
Chemical stability : 
Stability defined as 95% of the initial concentration
High Performance Liquid Chromatography - ultraviolet detector (HPLC-UV)
Other methods : 
Comments : 
No visual inspection
Degradation products identified and quantified
List of drugs
InjectionMitoxantrone dihydrochloride Anticancer drug
Stability in solutions Polyvinyl chloride NaCl 0,9% or Glucose 5% 0,04 & 0,4 mg/ml 23°C Not specified
7 Day
Stability in solutions Polyvinyl chloride NaCl 0,9% or Glucose 5% 0,04 & 0,4 mg/ml 4°C Protect from light
7 Day
  Mentions Légales