Last update :
08/12/2024
References   References 817  
Type : Journal

Research teams : Oslo - The National Hospital (Rikshospitalet), The National Hospital Pharmacy
Authors : Stendal TL, Klem W, Tonnesen HH, Kjonniksen I.
Title : Drug stability and pyridine generation in ceftazidime injection stored in an elastomeric infusion device.
Reference : Am J Health-Syst Pharm ; 55: 683-685. 1998

Level of Evidence : 
Level of evidence B
Physical stability : 
Visual examination 
Chemical stability : 
High Performance Liquid Chromatography - Diode Array detector (HPLD-DAD)
Stability defined as 90% of the initial concentration
Other methods : 
PH measurement 
Comments : 
Degradation products identified and quantified

List of drugs
injectionCeftazidime Antibiotic
Stability in solutions Polyisoprene elastomer Sodium chloride 0,9% 60 mg/ml -20°C Protect from light
14 Day
Stability in solutions Polyisoprene elastomer Sodium chloride 0,9% 60 mg/ml 4°C Protect from light
14 Day

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