Last update :
16/06/2024
References   References 80  
Type : Journal

Research teams : Columbus - The Ohio State University Hospitals, Department of Pharmacy
Authors : Nahata MC, Morosco RS, Hipple TF.
Title : Stability of cimetidine hydrochloride and of clindamycin phosphate in water for injection stored in glass vials at two temperatures.
Reference : Am J Hosp Pharm ; 50: 2559-2561. 1993

Level of Evidence : 
Level of evidence C
Physical stability : 
Visual examination 
Chemical stability : 
High Performance Liquid Chromatography - ultraviolet detector (HPLC-UV)
Stability defined as 95% of the initial concentration
Other methods : 
PH measurement 
Comments : 
Imperfect separation of the internal standard from the product under study or its degradation products, or understudied

List of drugs
InjectionCimetidine hydrochloride Antihistamine (H2)
Stability in solutions Glass Water for Injection 15 mg/ml 22°C Protect from light
14 Day
Stability in solutions Glass Water for Injection 15 mg/ml 4°C Protect from light
42 Day
InjectionClindamycin phosphate Antibiotic
Stability in solutions Glass Water for Injection 15 mg/ml 22°C Protect from light
91 Day
Stability in solutions Glass Water for Injection 15 mg/ml 4°C Protect from light
91 Day

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