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References   References 71  
Type : Journal
Research teams : Foster City - Gilead Sciences
Authors : Ennis RD, Dahl TC.
Title : Stability of cidofovir in 0.9% sodium chloride injection for five days.
Reference : Am J Health-Syst Pharm ; 54: 2204-2206. 1997
Level of Evidence : 
Level of evidence A+
Physical stability : 
Visual examination Particle counting 
Chemical stability : 
High Performance Liquid Chromatography - ultraviolet detector (HPLC-UV)
Stability defined as 95% of the initial concentration
Other methods : 
PH measurement Measurement of osmolality 
Comments : 
Stability indicating capability inadequately assessed
Method not shown but the article refers to a validated method
Degradation products not observed in real conditions
List of drugs
InjectionCidofovir Antiviral
Stability in solutions Polyvinyl chloride Sodium chloride 0,9% 0,2 & 8,1 mg/ml -20°C Protect from light
5 Day
Stability in solutions Polyvinyl chloride Sodium chloride 0,9% 0,2 & 8,1 mg/ml 2-8°C Protect from light
5 Day
Stability in solutions Polypropylene and polyethylene Sodium chloride 0,9% 0,2 & 8,1 mg/ml -20°C Protect from light
5 Day
Stability in solutions Polypropylene and polyethylene Sodium chloride 0,9% 0,2 & 8,1 mg/ml 2-8°C Protect from light
5 Day
  Mentions Légales