Last update :
12/06/2024
References   References 675  
Type : Journal

Research teams : Amsterdam - Academic Medical center, Department of Pharmacy
Authors : Roos PJ, Glerum JH, Meilink JW.
Title : Stability of sufentanil citrate in a portable pump reservoir, a glass container and a polyethylene container.
Reference : Pharm Weekbl [Sci] ; 14: 196-200. 1992

Level of Evidence : 
Level of evidence A
Physical stability : 
Visual examination 
Chemical stability : 
High Performance Liquid Chromatography - ultraviolet detector (HPLC-UV)
Stability defined as 95% of the initial concentration
Other methods : 
PH measurement 
Comments : 

List of drugs
InjectionSufentanil citrate Analgesic
Factors which affect stability Container Polyvinyl chloride[ 5 µg / ml ] Induces Adsorption
Stability in solutions Glass Sodium chloride 0,9% 0,005 mg/ml -20°C Protect from light
5 Day
Stability in solutions Glass Sodium chloride 0,9% 0,005 mg/ml 32°C Not specified
5 Day
Stability in solutions Glass Sodium chloride 0,9% 0,005 mg/ml 4°C Protect from light
5 Day
Stability in solutions Polyvinyl chloride Sodium chloride 0,9% 0,005 mg/ml 4°C Protect from light
5 Day
Stability in solutions Polyethylene Sodium chloride 0,9% 0,005 mg/ml -20°C Protect from light
5 Day
Stability in solutions Polyethylene Sodium chloride 0,9% 0,005 mg/ml 32°C Not specified
5 Day
Stability in solutions Polyethylene Sodium chloride 0,9% 0,005 mg/ml 4°C Protect from light
5 Day

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