Last update :
03/05/2024
References   References 65  
Type : Journal
Web link : http://www.ajhp.org/cgi/content/abstract/47/1/143

Research teams : New York - Memorial Sloan-Kettering Cancer Center
Authors : Duafala ME, Kleinberg ML, Nacov C, Flora KP, Hines J, Davis K, McDaniel A, Scott D.
Title : Stability of morphine sulfate in infusion devices and containers for intravenous administration.
Reference : Am J Hosp Pharm ; 47: 143-146. 1990

Level of Evidence : 
Level of evidence B
Physical stability : 
Visual examination 
Chemical stability : 
High Performance Liquid Chromatography - ultraviolet detector (HPLC-UV)
Stability defined as 90% of the initial concentration
Other methods : 
PH measurement 
Comments : 

List of drugs
InjectionMorphine sulfate Analgesic
Stability in solutions Glass Water for Injection 2 & 15 mg/ml 23°C-25°C Not specified
12 Day
Stability in solutions Glass Water for Injection 2 & 15 mg/ml 4°C Protect from light
12 Day
Stability in solutions Polyvinyl chloride Water for Injection 2 & 15 mg/ml 23°C-25°C Not specified
12 Day
Stability in solutions Polyvinyl chloride Water for Injection 2 & 15 mg/ml 4°C Protect from light
12 Day
Stability in solutions Polyisoprene elastomer Water for Injection 2 & 15 mg/ml 23°C-25°C Not specified
12 Day
Stability in solutions Polyisoprene elastomer Water for Injection 2 & 15 mg/ml 31°C Not specified
12 Day
Stability in solutions Polyisoprene elastomer Water for Injection 2 & 15 mg/ml 4°C Protect from light
12 Day

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