Last update :
28/04/2024
References   References 643  
Type : Journal

Research teams : Winnipeg - University of Manitoba, Faculty of Pharmacy
Authors : Seargeant LE, Kobrinsky NL, Sus CJ, Nazeravich DR.
Title : In vitro stability and compatibility of daunorubicin, cytarabine, and etoposide.
Reference : Cancer Treat Rep ; 71: 1189-1192. 1987

Level of Evidence : 
Level of evidence D
Physical stability : 
Visual examination 
Chemical stability : 
Stability defined as 90% of the initial concentration
High Performance Liquid Chromatography - ultraviolet detector (HPLC-UV)
Other methods : 
Comments : 
Stability indicating capability inadequately assessed
Repeatability / reproducibility / standard range: results not provided or results outside specified values
No visual inspection

List of drugs
InjectionCytarabine Anticancer drug
InjectionDaunorubicin hydrochloride Anticancer drug
InjectionEtoposide Anticancer drug
Stability of mixtures
Polyvinyl chloride NaCl 0,45% Glucose 5% 20°C Light
Injection Cytarabine 0,26 mg/ml
Injection Daunorubicin hydrochloride 0,03 mg/ml
Injection Etoposide 0,4 mg/ml
72 Hour

  Mentions Légales