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References   References 632  
Type : Journal
Research teams : Utrecht - Faculty of pharmacy, State university of Utrecht
Authors : Beijnen JH, Rosing H, De Vries PA, Underberg WJM.
Title : Stability of anthracycline antitumour agents in infusion fluids.
Reference : J Parenter Sci Technol ; 39: 220-222. 1985
Level of Evidence : 
Level of evidence C
Physical stability : 
Visual examination 
Chemical stability : 
Stability defined as 95% of the initial concentration
High Performance Liquid Chromatography - ultraviolet detector (HPLC-UV)
Other methods : 
Comments : 
Stability indicating capability inadequately assessed
Repeatability / reproducibility / standard range: results not provided or results outside specified values
No comments for the degradation products
List of drugs
InjectionDaunorubicin hydrochloride Anticancer drug
Stability in solutions Polypropylene NaCl 0,9% or Glucose 5% 0,1 mg/ml 25°C Protect from light
28 Day
Stability in solutions Polypropylene Ringer’s lactate solution 0,1 mg/ml 25°C Protect from light
28 Day
InjectionDoxorubicin hydrochloride Anticancer drug
Stability in solutions Polypropylene Glucose 5% 0,1 mg/ml 25°C Protect from light
28 Day
InjectionIdarubicin hydrochloride Anticancer drug
Stability in solutions Polypropylene NaCl 0,9% or Glucose 5% 0,1 mg/ml 25°C Protect from light
28 Day
Stability in solutions Polypropylene Ringer’s lactate solution 0,1 mg/ml 25°C Protect from light
28 Day
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